Jean-Marie Lehn

Jean Marie Lehn is a French Chemist who was awarded the Nobel Prize in Chemistry (1987) for his work on the synthesis of cryptands. Lehn is considered to be an innovator in the field of supramolecular chemistry.

In 1968 Lehn achieved the synthesis of a cage like molecule which had a cavity for other molecule to be lodged inside. Lehn called these molecules as cryptands and his work lead to the development of “supramolecular” chemistry which focuses on studying intermolecular attractions instead of bonds inside one molecule.

He was awarded Knight of the Ordre des Palmes Académiques (1989), Officer of the Ordre National du Mérite (1993), Commander of the Légion d’Honneur (1996), Österreichisches Ehrenzeichen für Wissenschaft und Kunst, (first class) (2001) and the ISA Medal for Science, (2007).

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Chemist CHEMIST (synthesis of the cryptands)
Jean-Marie Lehn
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1963 CNRS Bronze Medal

1968 FCS Adrian Prize

1972 CNRS Silver Medal

1978 FCS Berr Prize

1981 CNRS Gold Medal

1981 Gold Medal of the Pontifical Academy of Sciences

1982 SCS Philippus Paracelsus Medal

1983 EGU Alexander von Humboldt Medal

1987 Nobel Prize for Chemistry (with Donald J. Cram and Charles J. Pedersen)

1989 GCS Karl Ziegler Memorial Prize

1994 Ettore Majorana-Erice Science for Peace Prize

1997 Davy Medal

1997 FCS Lavoisier Medal

1998 SCI Messel Medal

2001 Austrian Medal for Science and the Arts

2003 Japan Society for the Promotion of Science Award

2007 ISA Medal for Science

1. Buchs Barbara; Fieber Wolfgang; Vigouroux-Elie Florence; Sreenivasachary Nampally; Lehn Jean-Marie; Herrmann Andreas Release of bioactive volatiles from supramolecular hydrogels: influence of reversible acylhydrazone formation on gel stability and volatile compound evaporation. Organic & biomolecular chemistry 2011;9(8):2906-19.

2. Aprahamian Marc; Bour Gaétan; Akladios Chérif Y; Fylaktakidou Konstantina; Greferath Ruth; Soler Luc; Marescaux Jacques; Egly Jean-Marc; Lehn Jean-Marie; Nicolau Claude Myo-InositolTrisPyroPhosphate treatment leads to HIF-1a suppression and eradication of early hepatoma tumors in rats. Chembiochem : a European journal of chemical biology 2011;12(5):777-83.

3. Ciesielski Artur; Stefankiewicz Artur R; Hanke Felix; Persson Mats; Lehn Jean-Marie; Samorì Paolo Rigid dimers formed through strong interdigitated H-bonds yield compact 1D supramolecular helical polymers. Small (Weinheim an der Bergstrasse, Germany) 2011;7(3):342-50.

4. Chaur Manuel N; Collado Daniel; Lehn Jean-Marie Configurational and constitutional information storage: multiple dynamics in systems based on pyridyl and acyl hydrazones. Chemistry (Weinheim an der Bergstrasse, Germany) 2011;17(1):248-58.

5. Koumbis Alexandros E; Duarte Carolina D; Nicolau Claude; Lehn Jean-Marie Tetrakisphosphates and bispyrophosphates of myo-inositol derivatives as allosteric effectors of human hemoglobin: Synthesis, molecular recognition, and oxygen release. ChemMedChem 2011;6(1):169-80.

6. Fylaktakidou Konstantina C; Duarte Carolina D; Koumbis Alexandros E; Nicolau Claude; Lehn Jean-Marie Polyphosphates and pyrophosphates of hexopyranoses as allosteric effectors of human hemoglobin: synthesis, molecular recognition, and effect on oxygen release. ChemMedChem 2011;6(1):153-68.

7. Kikkawa Yoshihiro; Kihara Hideyuki; Takahashi Mayuko; Kanesato Masatoshi; Balaban Teodor Silviu; Lehn Jean-Marie Two-dimensional structures of anthracene derivatives: photodimerization and host-guest chemistry. The journal of physical chemistry. B 2010;114(50):16718-22.

8. Duarte Carolina D; Greferath Ruth; Nicolau Claude; Lehn Jean-Marie myo-Inositol trispyrophosphate: a novel allosteric effector of hemoglobin with high permeation selectivity across the red blood cell plasma membrane. Chembiochem : a European journal of chemical biology 2010;11(18):2543-8.

9. Stadler Adrian-Mihail; Puntoriero Fausto; Nastasi Francesco; Campagna Sebastiano; Lehn Jean-Marie Ru(II) multinuclear metallosupramolecular rack-type architectures of polytopic hydrazone-based ligands: synthesis, structural features, absorption spectra, redox behavior, and near-infrared luminescence. Chemistry (Weinheim an der Bergstrasse, Germany) 2010;16(19):5645-60.

10. Godin Guillaume; Levrand Barbara; Trachsel Alain; Lehn Jean-Marie; Herrmann Andreas Reversible formation of aminals: a new strategy to control the release of bioactive volatiles from dynamic mixtures. Chemical communications (Cambridge, England) 2010;46(18):3125-7.

11. Stadler Adrian-Mihail; Ramírez Juan; Lehn Jean-Marie Control of relative direction and amplitude in extension/contraction motions of molecular strands induced by ion binding. Chemistry (Weinheim an der Bergstrasse, Germany) 2010;16(18):5369-78.

12. Saada Julien; Oudrhiri Noufissa; Bonnard Arnaud; de Lagausie Pascal; Aissaoui Abderrahim; Hauchecorne Michelle; Oury Jean-François; Aigrain Yves; Peuchmaur Michel; Lehn Jean-Marie; Lehn Pierre; Luton Dominique Combining keratinocyte growth factor transfection into the airways and tracheal occlusion in a fetal sheep model of congenital diaphragmatic hernia. The journal of gene medicine 2010;12(5):413-22.

13. Ruff Yves; Buhler Eric; Candau Sauveur-Jean; Kesselman Ellina; Talmon Yeshayahu; Lehn Jean-Marie Glycodynamers: dynamic polymers bearing oligosaccharides residues–generation, structure, physicochemical, component exchange, and lectin binding properties. Journal of the American Chemical Society 2010;132(8):2573-84.

14. Drahonovský Dusan; Lehn Jean-Marie Hemiacetals in dynamic covalent chemistry: formation, exchange, selection, and modulation processes. The Journal of organic chemistry 2009;74(21):8428-32.

15. Stefankiewicz Artur R; Rogez Guillaume; Harrowfield Jack; Drillon Marc; Lehn Jean-Marie Structural features directing the specificity and functionality of metallo-supramolecular grid-type architectures. Dalton transactions (Cambridge, England : 2003) 2009;(29):5787-802.

16. Ulrich Sébastien; Lehn Jean-Marie Adaptation and optical signal generation in a constitutional dynamic network. Chemistry (Weinheim an der Bergstrasse, Germany) 2009;15(23):5640-5.

17. Ulrich Sébastien; Lehn Jean-Marie Adaptation to shape switching by component selection in a constitutional dynamic system. Journal of the American Chemical Society 2009;131(15):5546-59.

18. Pace Giuseppina; Stefankiewicz Artur; Harrowfield Jack; Lehn Jean-Marie; Samorì Paolo Self-assembly of alkoxy-substituted bis(hydrazone)-based organic ligands and of a metallosupramolecular grid on graphite. Chemphyschem : a European journal of chemical physics and physical chemistry 2009;10(4):699-705.

19. Stefankiewicz Artur R; Lehn Jean-Marie Highly sensitive magnetic effects induced by hydrogen-bonding interactions in a high-spin metallosupramolecular Fe(4) (II) [2x2] grid-type complex. Chemistry (Weinheim an der Bergstrasse, Germany) 2009;15(11):2500-3.

20. Biolo Andreia; Greferath Ruth; Siwik Deborah A; Qin Fuzhong; Valsky Eugene; Fylaktakidou Konstantina C; Pothukanuri Srinivasu; Duarte Carolina D; Schwarz Richard P; Lehn Jean-Marie; Nicolau Claude; Colucci Wilson S Enhanced exercise capacity in mice with severe heart failure treated with an allosteric effector of hemoglobin, myo-inositol trispyrophosphate. Proceedings of the National Academy of Sciences of the United States of America 2009;106(6):1926-9.

21. Folmer-Andersen J Frantz; Lehn Jean-Marie Constitutional adaptation of dynamic polymers: hydrophobically driven sequence selection in dynamic covalent polyacylhydrazones. Angewandte Chemie (International ed. in English) 2009;48(41):7664-7.

22. Fujii Shunsuke; Lehn Jean-Marie Structural and functional evolution of a library of constitutional dynamic polymers driven by alkali metal ion recognition. Angewandte Chemie (International ed. in English) 2009;48(41):7635-8.

23. Ciesielski Artur; Schaeffer Gaël; Petitjean Anne; Lehn Jean-Marie; Samorì Paolo STM insight into hydrogen-bonded bicomponent 1D supramolecular polymers with controlled geometries at the liquid-solid interface. Angewandte Chemie (International ed. in English) 2009;48(11):2039-43.

24. Reutenauer P; Buhler E; Boul P J; Candau S J; Lehn J-M Room temperature dynamic polymers based on Diels-Alder chemistry. Chemistry (Weinheim an der Bergstrasse, Germany) 2009;15(8):1893-900.

25. Herrmann Andreas; Giuseppone Nicolas; Lehn Jean-Marie Electric-field triggered controlled release of bioactive volatiles from imine-based liquid crystalline phases. Chemistry (Weinheim an der Bergstrasse, Germany) 2009;15(1):117-24.

26. Castano Sabine; Delord Brigitte; Février Annie; Lehn Jean-Marie; Lehn Pierre; Desbat Bernard Brewster angle microscopy and PMIRRAS study of DNA interactions with BGTC, a cationic lipid used for gene transfer. Langmuir : the ACS journal of surfaces and colloids 2008;24(17):9598-606.

27. Chow Cheuk-Fai; Fujii Shunsuke; Lehn Jean-Marie Metallodynamers: neutral double-dynamic metallosupramolecular polymers. Chemistry, an Asian journal 2008;3(8-9):1324-35.

28. Ruff Yves; Lehn Jean-Marie Glycodynamers: dynamic analogs of arabinofuranoside oligosaccharides. Biopolymers 2008;89(5):486-96.

29. Petitjean Anne; Cuccia Louis A; Schmutz Marc; Lehn Jean-Marie Naphthyridine-based helical foldamers and macrocycles: synthesis, cation binding, and supramolecular assemblies. The Journal of organic chemistry 2008;73(7):2481-95.

30. Sreenivasachary Nampally; Lehn Jean-Marie Structural selection in G-quartet-based hydrogels and controlled release of bioactive molecules. Chemistry, an Asian journal 2008;3(1):134-9.

31. Ruff Yves; Lehn Jean-Marie Glycodynamers: fluorescent dynamic analogues of polysaccharides. Angewandte Chemie (International ed. in English) 2008;47(19):3556-9.

32. Pace Giuseppina; Petitjean Anne; Lalloz-Vogel Marie-Noëlle; Harrowfield Jack; Lehn Jean-Marie; Samorì Paolo Subnanometer-resolved patterning of bicomponent self-assembled monolayers on Au(111). Angewandte Chemie (International ed. in English) 2008;47(13):2484-8.

33. Ulrich Sébastien; Lehn Jean-Marie Reversible switching between macrocyclic and polymeric states by morphological control in a constitutional dynamic system. Angewandte Chemie (International ed. in English) 2008;47(12):2240-3.

34. Giuseppone Nicolas; Schmitt Jean-Louis; Allouche Lionel; Lehn Jean-Marie DOSY NMR experiments as a tool for the analysis of constitutional and motional dynamic processes: implementation for the driven evolution of dynamic combinatorial libraries of helical strands. Angewandte Chemie (International ed. in English) 2008;47(12):2235-9.

35. Buhler Eric; Candau Sauveur-Jean; Kolomiets Elena; Lehn Jean-Marie Dynamical properties of semidilute solutions of hydrogen-bonded supramolecular polymers. Physical review. E, Statistical, nonlinear, and soft matter physics 2007;76(6 Pt 1):061804.

36. Chow Cheuk-Fai; Fujii Shunsuke; Lehn Jean-Marie Crystallization-driven constitutional changes of dynamic polymers in response to neat/solution conditions. Chemical communications (Cambridge, England) 2007;(42):4363-5.

37. Ono Takashi; Fujii Shunsuke; Nobori Tadahito; Lehn Jean-Marie Optodynamers: expression of color and fluorescence at the interface between two films of different dynamic polymers. Chemical communications (Cambridge, England) 2007;(42):4360-2.

38. Desigaux Léa; Sainlos Matthieu; Lambert Olivier; Chevre Raphael; Letrou-Bonneval Emilie; Vigneron Jean-Pierre; Lehn Pierre; Lehn Jean-Marie; Pitard Bruno Self-assembled lamellar complexes of siRNA with lipidic aminoglycoside derivatives promote efficient siRNA delivery and interference. Proceedings of the National Academy of Sciences of the United States of America 2007;104(42):16534-9.

39. Buhler Eric; Sreenivasachary Nampally; Candau Sauveur-Jean; Lehn Jean-Marie Modulation of the supramolecular structure of G-quartet assemblies by dynamic covalent decoration. Journal of the American Chemical Society 2007;129(33):10058-9.

40. Sihn Gabin; Walter Thomas; Klein Jean-Claude; Queguiner Isabelle; Iwao Hiroshi; Nicolau Claude; Lehn Jean-Marie; Corvol Pierre; Gasc Jean-Marie Anti-angiogenic properties of myo-inositol trispyrophosphate in ovo and growth reduction of implanted glioma. FEBS letters 2007;581(5):962-6.

41. Lehn Jean-Marie A natural selection. Chemical communications (Cambridge, England) 2007;(7):C15.

42. Lehn Jean-Marie A natural selection. Organic & biomolecular chemistry 2007;5(4):C15.

43. Lehn Jean-Marie A natural selection. Dalton transactions (Cambridge, England : 2003) 2007;(7):C15.

44. Lehn Jean-Marie From supramolecular chemistry towards constitutional dynamic chemistry and adaptive chemistry. Chemical Society reviews 2007;36(2):151-60.

45. Ramírez Juan; Stadler Adrian-Mihail; Kyritsakas Nathalie; Lehn Jean-Marie Solvent-modulated reversible conversion of a [2 x 2]-grid into a pincer-like complex. Chemical communications (Cambridge, England) 2007;(3):237-9.

46. Ono Takashi; Fujii Shunsuke; Nobori Tadahito; Lehn Jean-Marie Soft-to-hard transformation of the mechanical properties of dynamic covalent polymers through component incorporation. Chemical communications (Cambridge, England) 2007;(1):46-8.

47. Balaban Teodor Silviu; Berova Nina; Drain Charles Michael; Hauschild Robert; Huang Xuefei; Kalt Heinz; Lebedkin Sergei; Lehn Jean-Marie; Nifaitis Fotis; Pescitelli Gennaro; Prokhorenko Valentyn I; Riedel Gernot; Smeureanu Gabriela; Zeller Joachim Syntheses and energy transfer in multiporphyrinic arrays self-assembled with hydrogen-bonding recognition groups and comparison with covalent steroidal models. Chemistry (Weinheim an der Bergstrasse, Germany) 2007;13(30):8411-27.

48. Loiseau Frédérique; Nastasi Francesco; Stadler Adrian-Mihail; Campagna Sebastiano; Lehn Jean-Marie Molecular wire type behavior of polycationic multinuclear rack-type RuII complexes of polytopic hydrazone-based ligands. Angewandte Chemie (International ed. in English) 2007;46(32):6144-7.

49. Chow Cheuk-Fai; Fujii Shunsuke; Lehn Jean-Marie Metallodynamers: neutral dynamic metallosupramolecular polymers displaying transformation of mechanical and optical properties on constitutional exchange. Angewandte Chemie (International ed. in English) 2007;46(26):5007-10.

50. Kolomiets Elena; Berl Volker; Lehn Jean-Marie Chirality induction and protonation-induced molecular motions in helical molecular strands. Chemistry (Weinheim an der Bergstrasse, Germany) 2007;13(19):5466-79.

51. Stadler Adrian-Mihail; Kyritsakas Nathalie; Vaughan Gavin; Lehn Jean-Marie Solid-state self-assembly of polymeric double helicates leading to linear arrays of silver(I) ions and reversible strand/double helix interconversion in solution. Chemistry (Weinheim an der Bergstrasse, Germany) 2007;13(1):59-68.

52. Giuseppone Nicolas; Schmitt Jean-Louis; Lehn Jean-Marie Driven evolution of a constitutional dynamic library of molecular helices toward the selective generation of [2 x 2] gridlike arrays under the pressure of metal ion coordination. Journal of the American Chemical Society 2006;128(51):16748-63.

53. Setnicka Vladimír; Urbanová Marie; Volka Karel; Nampally Sreenivasachary; Lehn Jean-Marie Investigation of guanosine-quartet assemblies by vibrational and electronic circular dichroism spectroscopy, a novel approach for studying supramolecular entities. Chemistry (Weinheim an der Bergstrasse, Germany) 2006;12(34):8735-43.

54. Sreenivasachary Nampally; Hickman David T; Sarazin Dominique; Lehn Jean-Marie DyNAs: constitutional dynamic nucleic acid analogues. Chemistry (Weinheim an der Bergstrasse, Germany) 2006;12(33):8581-8.

55. Ruben Mario; Lehn Jean-Marie; Müller Paul Addressing metal centres in supramolecular assemblies. Chemical Society reviews 2006;35(11):1056-67.

56. Haluska Christopher K; Riske Karin A; Marchi-Artzner Valérie; Lehn Jean-Marie; Lipowsky Reinhard; Dimova Rumiana Time scales of membrane fusion revealed by direct imaging of vesicle fusion with high temporal resolution. Proceedings of the National Academy of Sciences of the United States of America 2006;103(43):15841-6.

57. Kieda Claudine; Greferath Ruth; Crola da Silva Claire; Fylaktakidou Konstantina C; Lehn Jean-Marie; Nicolau Claude Suppression of hypoxia-induced HIF-1alpha and of angiogenesis in endothelial cells by myo-inositol trispyrophosphate-treated erythrocytes. Proceedings of the National Academy of Sciences of the United States of America 2006;103(42):15576-81.

58. Skene W G; Berl Volker; Risler Hélène; Khoury Richard; Lehn Jean-Marie Selective product amplification of thymine photodimer by recognition-directed supramolecular assistance. Organic & biomolecular chemistry 2006;4(19):3652-63.

59. Allouche Lionel; Marquis Annie; Lehn Jean-Marie Discrimination of metallosupramolecular architectures in solution by using diffusion ordered spectroscopy (DOSY) experiments: double-stranded helicates of different lengths. Chemistry (Weinheim an der Bergstrasse, Germany) 2006;12(28):7520-5.

60. Mourran Ahmed; Ziener Ulrich; Möller Martin; Suarez Maurizio; Lehn Jean-Marie Homo- and heteroassemblies of lactim/lactam recognition patterns on highly ordered pyrolytic graphite: An STM investigation. Langmuir : the ACS journal of surfaces and colloids 2006;22(18):7579-86.

61. Waldmann Oliver; Ruben Mario; Ziener Ulrich; Müller Paul; Lehn Jean M Supramolecular Co(II)-[2 x 2] grids: metamagnetic behavior in a single molecule. Inorganic chemistry 2006;45(16):6535-40.

62. Lehn Jean-Marie Conjecture: imines as unidirectional photodriven molecular motors-motional and constitutional dynamic devices. Chemistry (Weinheim an der Bergstrasse, Germany) 2006;12(23):5910-5.

63. Levrand Barbara; Ruff Yves; Lehn Jean-Marie; Herrmann Andreas Controlled release of volatile aldehydes and ketones by reversible hydrazone formation–classical” profragrances are getting dynamic. Chemical communications (Cambridge, England) 2006;(28):2965-7.

64. Marquis Annie; Smith Virginia; Harrowfield Jack; Lehn Jean-Marie; Herschbach Haiko; Sanvito Rossella; Leize-Wagner Emmanuelle; Van Dorsselaer Alain Messages in molecules: ligand/cation coding and self-recognition in a constitutionally dynamic system of heterometallic double helicates. Chemistry (Weinheim an der Bergstrasse, Germany) 2006;12(21):5632-41.

65. Pei Zhichao; Larsson Rikard; Aastrup Teodor; Anderson Henrik; Lehn Jean-Marie; Ramström Olof Quartz crystal microbalance bioaffinity sensor for rapid identification of glycosyldisulfide lectin inhibitors from a dynamic combinatorial library. Biosensors & bioelectronics 2006;22(1):42-8.

66. Giuseppone Nicolas; Lehn Jean-Marie Electric-field modulation of component exchange in constitutional dynamic liquid crystals. Angewandte Chemie (International ed. in English) 2006;45(28):4619-24.

67. Stadler Adrian-Mihail; Kyritsakas Nathalie; Graff Roland; Lehn Jean-Marie Formation of RACK- and grid-type metallosupramolecular architectures and generation of molecular motion by reversible uncoiling of helical ligand strands. Chemistry (Weinheim an der Bergstrasse, Germany) 2006;12(17):4503-22.

68. Linke-Schaetzel Myriam; Anson Christopher E; Powell Annie K; Buth Gernot; Palomares Emilio; Durrant James D; Balaban Teodor Silviu; Lehn Jean-Marie Dynamic chemical devices: photoinduced electron transfer and its ion-triggered switching in nanomechanical butterfly-type bis(porphyrin)terpyridines. Chemistry (Weinheim an der Bergstrasse, Germany) 2006;12(7):1931-40.

69. Giuseppone Nicolas; Lehn Jean-Marie Protonic and temperature modulation of constituent expression by component selection in a dynamic combinatorial library of imines. Chemistry (Weinheim an der Bergstrasse, Germany) 2006;12(6):1715-22.

70. Giuseppone Nicolas; Fuks Gad; Lehn Jean-Marie Tunable fluorene-based dynamers through constitutional dynamic chemistry. Chemistry (Weinheim an der Bergstrasse, Germany) 2006;12(6):1723-35.

71. Kaiser Markus; Sainlos Matthieu; Lehn Jean-Marie; Bombard Sophie; Teulade-Fichou Marie-Paule Aminoglycoside-quinacridine conjugates: towards recognition of the P6.1 element of telomerase RNA. Chembiochem : a European journal of chemical biology 2006;7(2):321-9.

72. Ghoussoub Assaad; Lehn Jean-Marie Dynamic sol-gel interconversion by reversible cation binding and release in G-quartet-based supramolecular polymers. Chemical communications (Cambridge, England) 2005;(46):5763-5.

73. Alam Mohammad Sahabul; Strömsdörfer Stefan; Dremov Viacheslav; Müller Paul; Kortus Jens; Ruben Mario; Lehn Jean-Marie Addressing the metal centers of [2x2] CoII4 grid-type complexes by STM/STS. Angewandte Chemie (International ed. in English) 2005;44(48):7896-900.

74. Petitjean Anne; Kyritsakas Nathalie; Lehn Jean-Marie Ion-triggered multistate molecular switching device based on regioselective coordination-controlled ion binding. Chemistry (Weinheim an der Bergstrasse, Germany) 2005;11(23):6818-28.

75. Stadler Adrian-Mihail; Puntoriero Fausto; Campagna Sebastiano; Kyritsakas Nathalie; Welter Richard; Lehn Jean-Marie Synthesis, structural features, absorption spectra, redox behaviour and luminescence properties of ruthenium(ii) rack-type dinuclear complexes with ditopic, hydrazone-based ligands. Chemistry (Weinheim an der Bergstrasse, Germany) 2005;11(13):3997-4009.

76. Sainlos Matthieu; Hauchecorne Michelle; Oudrhiri Noufissa; Zertal-Zidani Samia; Aissaoui Abderrahim; Vigneron Jean-Pierre; Lehn Jean-Marie; Lehn Pierre Kanamycin A-derived cationic lipids as vectors for gene transfection. Chembiochem : a European journal of chemical biology 2005;6(6):1023-33.

77. Sreenivasachary Nampally; Lehn Jean-Marie Gelation-driven component selection in the generation of constitutional dynamic hydrogels based on guanine-quartet formation. Proceedings of the National Academy of Sciences of the United States of America 2005;102(17):5938-43.

78. Giuseppone Nicolas; Schmitt Jean-Louis; Schwartz Evan; Lehn Jean-Marie Scandium(III) catalysis of transimination reactions. Independent and constitutionally coupled reversible processes. Journal of the American Chemical Society 2005;127(15):5528-39.

79. Uppadine Lindsay H; Gisselbrecht Jean-Paul; Kyritsakas Nathalie; Nättinen Kalle; Rissanen Kari; Lehn Jean-Marie Mixed-valence, mixed-spin-state, and heterometallic [2x2] grid-type arrays based on heteroditopic hydrazone ligands: synthesis and electrochemical features. Chemistry (Weinheim an der Bergstrasse, Germany) 2005;11(8):2549-65.

80. Ono Takashi; Nobori Tadahito; Lehn Jean-Marie Dynamic polymer blends–component recombination between neat dynamic covalent polymers at room temperature. Chemical communications (Cambridge, England) 2005;(12):1522-4.

81. Kolomiets Elena; Lehn Jean-Marie Double dynamers: molecular and supramolecular double dynamic polymers. Chemical communications (Cambridge, England) 2005;(12):1519-21.

82. Fylaktakidou Konstantina C; Lehn Jean-Marie; Greferath Ruth; Nicolau Claude Inositol tripyrophosphate: a new membrane permeant allosteric effector of haemoglobin. Bioorganic & medicinal chemistry letters 2005;15(6):1605-8.

83. Ikeda Masato; Nobori Tadahito; Schmutz Marc; Lehn Jean-Marie Hierarchical self-assembly of a bow-shaped molecule bearing self-complementary hydrogen bonding sites into extended supramolecular assemblies. Chemistry (Weinheim an der Bergstrasse, Germany) 2005;11(2):662-8.

84. Boul Peter J; Reutenauer Philippe; Lehn Jean-Marie Reversible Diels-Alder reactions for the generation of dynamic combinatorial libraries. Organic letters 2005;7(1):15-8.

85. Martin B; Sainlos M; Aissaoui A; Oudrhiri N; Hauchecorne M; Vigneron J-P; Lehn J-M; Lehn P The design of cationic lipids for gene delivery. Current pharmaceutical design 2005;11(3):375-94.

86. Ruben Mario; Ziener Ulrich; Lehn Jean-Marie; Ksenofontov Vadim; Gütlich Philipp; Vaughan Gavin B M Hierarchical self-assembly of supramolecular spintronic modules into 1D- and 2D-architectures with emergence of magnetic properties. Chemistry (Weinheim an der Bergstrasse, Germany) 2004;11(1):94-100.

87. Richard Antoine; Marchi-Artzner Valérie; Lalloz Marie-Noëlle; Brienne Marie-Josèphe; Artzner Franck; Gulik-Krzywicki Thaddée; Guedeau-Boudeville Marie-Alice; Lehn Jean-Marie Fusogenic supramolecular vesicle systems induced by metal ion binding to amphiphilic ligands. Proceedings of the National Academy of Sciences of the United States of America 2004;101(43):15279-84.

88. Aissaoui Abderrahim; Martin Benjamin; Kan Erwan; Oudrhiri Noufissa; Hauchecorne Michelle; Vigneron Jean-Pierre; Lehn Jean-Marie; Lehn Pierre Novel cationic lipids incorporating an acid-sensitive acylhydrazone linker: synthesis and transfection properties. Journal of medicinal chemistry 2004;47(21):5210-23.

89. Giuseppone Nicolas; Lehn Jean-Marie Constitutional dynamic self-sensing in a zinc(II)/polyiminofluorenes system. Journal of the American Chemical Society 2004;126(37):11448-9.

90. Stadler Adrian-Mihail; Kyritsakas Nathalie; Lehn Jean-Marie Reversible folding/unfolding of linear molecular strands into helical channel-like complexes upon proton-modulated binding and release of metal ions. Chemical communications (Cambridge, England) 2004;(18):2024-5.

91. Giuseppone Nicolas; Schmitt Jean-Louis; Lehn Jean-Marie Generation of dynamic constitutional diversity and driven evolution in helical molecular strands under Lewis acid catalyzed component exchange. Angewandte Chemie (International ed. in English) 2004;43(37):4902-6.

92. Delgado Ledesma Salvador; Ponce Ortiz Rocío; Ruiz Delgado Mari Carmen; Vida Yolanda; Pérez-Inestrosa E; Casado Juan; Hernández Víctor; Kim Oh-Kil; Lehn Jean-Marie; López Navarrete Juan T Vibrational and quantum-chemical study of nonlinear optical chromophores containing dithienothiophene as the electron relay. Chemistry (Weinheim an der Bergstrasse, Germany) 2004;10(15):3805-16.

93. Petitjean Anne; Nierengarten Hélène; van Dorsselaer Alain; Lehn Jean-Marie Self-organization of oligomeric helical stacks controlled by substrate binding in a tobacco mosaic virus like self-assembly process. Angewandte Chemie (International ed. in English) 2004;43(28):3695-9.

94. Ruben Mario; Rojo Javier; Romero-Salguero Francisco J; Uppadine Lindsay H; Lehn Jean-Marie Grid-type metal ion architectures: functional metallosupramolecular arrays. Angewandte Chemie (International ed. in English) 2004;43(28):3644-62.

95. Barboiu Mihail; Prodi Luca; Montalti Marco; Zaccheroni Nelsi; Kyritsakas Nathalie; Lehn Jean-Marie Dynamic chemical devices: modulation of photophysical properties by reversible, ion-triggered, and proton-fuelled nanomechanical shape-flipping molecular motions. Chemistry (Weinheim an der Bergstrasse, Germany) 2004;10(12):2953-9.

96. Petitjean Anne; Khoury Richard G; Kyritsakas Nathalie; Lehn Jean-Marie Dynamic devices. Shape switching and substrate binding in ion-controlled nanomechanical molecular tweezers. Journal of the American Chemical Society 2004;126(21):6637-47.

97. Skene Williams G; Lehn Jean-Marie P Dynamers: polyacylhydrazone reversible covalent polymers, component exchange, and constitutional diversity. Proceedings of the National Academy of Sciences of the United States of America 2004;101(22):8270-5.

98. Marchi-Artzner Valérie; Brienne Marie-Josephe; Gulik-Krzywicki Thaddée; Dedieu Jean-Claude; Lehn Jean-Marie Selective complexation and transport of europium ions at the interface of vesicles. Chemistry (Weinheim an der Bergstrasse, Germany) 2004;10(9):2342-50.

99. Ramström Olof; Lohmann Sophie; Bunyapaiboonsri Taridaporn; Lehn Jean-Marie Dynamic combinatorial carbohydrate libraries: probing the binding site of the concanavalin A lectin. Chemistry (Weinheim an der Bergstrasse, Germany) 2004;10(7):1711-5.

100. Uppadine Lindsay H; Gisselbrecht Jean-Paul; Lehn Jean-Marie Protonic modulation of redox properties in ionisable [2 x 2] grid-like metalloarrays. Chemical communications (Cambridge, England) 2004;(6):718-9.

101. Luton Dominique; Oudrhiri Noufissa; de Lagausie Pascal; Aissaoui Abderrahim; Hauchecorne Michelle; Julia Sébastien; Oury Jean-François; Aigrain Yves; Peuchmaur Michel; Vigneron Jean-Pierre; Lehn Jean-Marie; Lehn Pierre Gene transfection into fetal sheep airways in utero using guanidinium-cholesterol cationic lipids. The journal of gene medicine 2004;6(3):328-36.

102. Odriozola Ibon; Kyritsakas Nathalie; Lehn Jean-Marie Structural codons: linearity/helicity interconversion by pyridine/pyrimidine exchange in molecular strands. Chemical communications (Cambridge, England) 2004;(1):62-3.

103. Uppadine Lindsay H; Lehn Jean-Marie Three-level synthetic strategy towards mixed-valence and heterometallic [2 x 2] gridlike arrays. Angewandte Chemie (International ed. in English) 2004;43(2):240-3.

104. Hajri Amor; Wack Séverine; Lehn Pierre; Vigneron Jean-Pierre; Lehn Jean-Marie; Marescaux Jacques; Aprahamian Marc Combined suicide gene therapy for pancreatic peritoneal carcinomatosis using BGTC liposomes. Cancer gene therapy 2004;11(1):16-27.

105. Bunyapaiboonsri Taridaporn; Ramström Helena; Ramström Olof; Haiech Jacques; Lehn Jean-Marie Generation of bis-cationic heterocyclic inhibitors of Bacillus subtilis HPr kinase/phosphatase from a ditopic dynamic combinatorial library. Journal of medicinal chemistry 2003;46(26):5803-11.

106. Kolomiets Elena; Berl Volker; Odriozola Ibon; Stadler Adrian-Mihail; Kyritsakas Nathalie; Lehn Jean-Marie Contraction/extension molecular motion by protonation/deprotonation induced structural switching of pyridine derived oligoamides. Chemical communications (Cambridge, England) 2003;(23):2868-9.

107. Bassani Dario M; Lehn Jean-Marie; Serroni Scolastica; Puntoriero Fausto; Campagna Sebastiano Homo- and heterometallic [2x2] grid arrays containing RuII, OsII, and FeII subunits and their mononuclear RuII and OsII precursors: synthesis, absorption spectra, redox behavior, and luminescence properties. Chemistry (Weinheim an der Bergstrasse, Germany) 2003;9(23):5936-46.

108. David Arnaud; Bleimling Nathalie; Beuck Christine; Lehn Jean-Marie; Weinhold Elmar; Teulade-Fichou Marie-Paule DNA mismatch-specific base flipping by a bisacridine macrocycle. Chembiochem : a European journal of chemical biology 2003;4(12):1326-31.

109. Skene William G; Couzigné Emilie; Lehn Jean-Marie Supramolecular control of the template-induced selective photodimerization of 4-methyl-7-O-hexylcoumarin. Chemistry (Weinheim an der Bergstrasse, Germany) 2003;9(22):5560-6.

110. Nitschke Jonathan R; Lehn Jean-Marie Self-organization by selection: generation of a metallosupramolecular grid architecture by selection of components in a dynamic library of ligands. Proceedings of the National Academy of Sciences of the United States of America 2003;100(21):11970-4.

111. Ruben Mario; Breuning Esther; Lehn Jean-Marie; Ksenofontov Vadim; Renz Franz; Gütlich Philip; Vaughan Gavin B M Supramolecular spintronic devices: spin transitions and magnetostructural correlations in [Fe4IIL4]8+ [2x2]-grid-type complexes. Chemistry (Weinheim an der Bergstrasse, Germany) 2003;9(18):4422-9.

112. Barboiu Mihail; Vaughan Gavin; Graff Roland; Lehn Jean-Marie Self-assembly, structure, and dynamic interconversion of metallosupramolecular architectures generated by Pb(II) binding-induced unfolding of a helical ligand. Journal of the American Chemical Society 2003;125(34):10257-65.

113. Ruben Mario; Lehn Jean-Marie; Vaughan Gavin Synthesis of ionisable [2 x 2] grid-type metallo-arrays and reversible protonic modulation of the optical properties of the [Co4(II)L4]8+ species. Chemical communications (Cambridge, England) 2003;(12):1338-9.

114. Teulade-Fichou M P; Hounsou C; Guittat L; Mergny J L; Alberti P; Carrasco C; Bailly C; Lehn J M; Wilson W D Molecular recognition of quadruplex DNA by quinacridine derivatives. Nucleosides, nucleotides & nucleic acids 2003;22(5-8):1483-5.

115. Teulade-Fichou Marie-Paule; Carrasco Carolina; Guittat Lionel; Bailly Christian; Alberti Patrizia; Mergny Jean-Louis; David Arnaud; Lehn Jean-Marie; Wilson W David Selective recognition of G-qQuadruplex telomeric DNA by a bis(quinacridine) macrocycle. Journal of the American Chemical Society 2003;125(16):4732-40.

116. Balaban Teodor Silviu; Goddard Richard; Linke-Schaetzel Myriam; Lehn Jean-Marie 2-Aminopyrimidine directed self-assembly of zinc porphyrins containing bulky 3,5-di-tert-butylphenyl groups. Journal of the American Chemical Society 2003;125(14):4233-9.

117. Barboiu Mihail; Vaughan Gavin; Kyritsakas Nathalie; Lehn Jean-Marie Dynamic chemical devices: generation of reversible extension/contraction molecular motion by ion-triggered single/double helix interconversion. Chemistry (Weinheim an der Bergstrasse, Germany) 2003;9(3):763-9.

118. Ruben Mario; Breuning Esther; Barboiu Mihail; Gisselbrecht Jean-Paul; Lehn Jean-Marie Functional supramolecular devices: [M4IIL4]8+ [2 x 2]-grid-type complexes as multilevel molecular electronic species. Chemistry (Weinheim an der Bergstrasse, Germany) 2003;9(1):291-9.

119. Ramström Olof; Bunyapaiboonsri Taridaporn; Lohmann Sophie; Lehn Jean-Marie Chemical biology of dynamic combinatorial libraries. Biochimica et biophysica acta 2002;1572(2-3):178-86.

120. Belmont Philippe; Aissaoui Abderrahim; Hauchecorne Michelle; Oudrhiri Noufissa; Petit Laure; Vigneron Jean-Pierre; Lehn Jean-Marie; Lehn Pierre Aminoglycoside-derived cationic lipids as efficient vectors for gene transfection in vitro and in vivo. The journal of gene medicine 2002;4(5):517-26.

121. Vincent Stéphane P; Lehn Jean-Marie; Lazarte Jaime; Nicolau Claude Transport of the highly charged myo-inositol hexakisphosphate molecule across the red blood cell membrane: a phase transfer and biological study. Bioorganic & medicinal chemistry 2002;10(9):2825-34.

122. Marquis Annie; Kintzinger Jean-Pierre; Graff Roland; Baxter Paul N W; Lehn Jean-Marie Mechanistic features, cooperativity, and robustness in the self-assembly of multicomponent silver(I) grid-type metalloarchitectures. Angewandte Chemie (International ed. in English) 2002;41(15):2760-4.

123. Breuning Esther; Hanan Garry S; Romero-Salguero Francisco J; Garcia Ana M; Baxter Paul N W; Lehn Jean-Marie; Wegelius Elina; Rissanen Kari; Nierengarten Hélène; van Dorsselaer Alain Self-assembly, characterisation, and crystal structure of multinuclear metal complexes of the [2 x 3] and [3 x 3] grid-type. Chemistry (Weinheim an der Bergstrasse, Germany) 2002;8(15):3458-66.

124. Cuccia Louis A; Ruiz Eliseo; Lehn Jean-Marie; Homo Jean-Claude; Schmutz Marc Helical self-organization and hierarchical self-assembly of an oligoheterocyclic pyridine-pyridazine strand into extended supramolecular fibers. Chemistry (Weinheim an der Bergstrasse, Germany) 2002;8(15):3448-57.

125. Barboiu Mihail; Lehn Jean-Marie Dynamic chemical devices: modulation of contraction/extension molecular motion by coupled-ion binding/pH change-induced structural switching. Proceedings of the National Academy of Sciences of the United States of America 2002;99(8):5201-6.

126. Lehn Jean-Marie Toward complex matter: supramolecular chemistry and self-organization. Proceedings of the National Academy of Sciences of the United States of America 2002;99(8):4763-8.

127. Petitjean Anne; Cuccia Louis A; Lehn Jean-Marie; Nierengarten Hélène; Schmutz Marc Cation-promoted hierarchical formation of supramolecular assemblies of self-organized helical molecular components. Angewandte Chemie (International ed. in English) 2002;41(7):1195-8.

128. Mayor M; Büschel M; Fromm K M; Lehn J-M; Daub J Electron transfer through bridging molecular structures. Annals of the New York Academy of Sciences 2002;960():16-28.

129. Lehn Jean-Marie Toward self-organization and complex matter. Science (New York, N.Y.) 2002;295(5564):2400-3.

130. Berl Volker; Schmutz Marc; Krische Michael J; Khoury Richard G; Lehn Jean-Marie Supramolecular polymers generated from heterocomplementary monomers linked through multiple hydrogen-bonding arrays–formation, characterization, and properties. Chemistry (Weinheim an der Bergstrasse, Germany) 2002;8(5):1227-44.

131. Ziener Ulrich; Lehn Jean-Marie; Mourran Ahmed; Möller Martin Supramolecular assemblies of a bis(terpyridine) ligand and of its [2x2] grid-type Zn(II) and Co(II) complexes on highly ordered pyrolytic graphite. Chemistry (Weinheim an der Bergstrasse, Germany) 2002;8(4):951-7.

132. Aissaoui Abderrahim; Oudrhiri Noufissa; Petit Laure; Hauchecorne Michelle; Kan Erwan; Sainlos Matthieu; Julia Sébastien; Navarro Jean; Vigneron Jean-Pierre; Lehn Jean-Marie; Lehn Pierre Progress in gene delivery by cationic lipids: guanidinium-cholesterol-based systems as an example. Current drug targets 2002;3(1):1-16.

133. Ramström Olof; Lehn Jean-Marie Drug discovery by dynamic combinatorial libraries. Nature reviews. Drug discovery 2002;1(1):26-36.

134. Nierengarten Hélène; Leize Emmanuelle; Breuning Esther; Garcia Ana; Romero-Salguero Francisco; Rojo Javier; Lehn Jean-Marie; Van Dorsselaer Alain Characterization of multimetallic grid-type complexes by electrospray mass spectrometry. Journal of mass spectrometry : JMS 2002;37(1):56-62.

135. Alberti P; Ren J; Teulade-Fichou M P; Guittat L; Riou J F; Chaires J; Hélène C; Vigneron J P; Lehn J M; Mergny J L Interaction of an acridine dimer with DNA quadruplex structures. Journal of biomolecular structure & dynamics 2001;19(3):505-13.

136. Teulade-Fichou M P; Perrin D; Boutorine A; Polverari D; Vigneron J P; Lehn J M; Sun J S; Garestier T; Helene C Direct photocleavage of HIV-DNA by quinacridine derivatives triggered by triplex formation. Journal of the American Chemical Society 2001;123(38):9283-92.

137. Funeriu D P; Rissanen K; Lehn J M Dominant/recessive behavior in the expression of molecular information: self-assembly of inorganic macrocyclic architectures containing coordinatively unsaturated ligands. Proceedings of the National Academy of Sciences of the United States of America 2001;98(19):10546-51.

138. Pitard B; Oudrhiri N; Lambert O; Vivien E; Masson C; Wetzer B; Hauchecorne M; Scherman D; Rigaud J L; Vigneron J P; Lehn J M; Lehn P Sterically stabilized BGTC-based lipoplexes: structural features and gene transfection into the mouse airways in vivo. The journal of gene medicine 2001;3(5):478-87.

139. Berl V; Huc I; Khoury R G; Lehn J M Helical molecular programming: supramolecular double helices by dimerization of helical oligopyridine-dicarboxamide strands. Chemistry (Weinheim an der Bergstrasse, Germany) 2001;7(13):2810-20.

140. Berl V; Huc I; Khoury R G; Lehn J M Helical molecular programming: folding of oligopyridine-dicarboxamides into molecular single helices. Chemistry (Weinheim an der Bergstrasse, Germany) 2001;7(13):2798-809.

141. Bunyapaiboonsri T; Ramström O; Lohmann S; Lehn J M; Peng L; Goeldner M Dynamic deconvolution of a pre-equilibrated dynamic combinatorial library of acetylcholinesterase inhibitors. Chembiochem : a European journal of chemical biology 2001;2(6):438-44.

142. Sukhanova A; Dêvy J; Pluot M; Bradley J C; Vigneron J P; Jardillier J C; Lehn J M; Nabiev I Human DNA topoisomerase I inhibitory activities of synthetic polyamines: relation to DNA aggregation. Bioorganic & medicinal chemistry 2001;9(5):1255-68.

143. Lehn J M; Eliseev A V Dynamic combinatorial chemistry. Science (New York, N.Y.) 2001;291(5512):2331-2.

144. Mayor M; Büschel M; Fromm K M; Lehn J M; Daub J Electron transfer through molecular bridges between reducible pentakis(thiophenyl)benzene subunits. Chemistry (Weinheim an der Bergstrasse, Germany) 2001;7(6):1266-72.

145. Mergny J L; Lacroix L; Teulade-Fichou M P; Hounsou C; Guittat L; Hoarau M; Arimondo P B; Vigneron J P; Lehn J M; Riou J F; Garestier T; Hélène C Telomerase inhibitors based on quadruplex ligands selected by a fluorescence assay. Proceedings of the National Academy of Sciences of the United States of America 2001;98(6):3062-7.

146. Patel M; Vivien E; Hauchecorne M; Oudrhiri N; Ramasawmy R; Vigneron J P; Lehn P; Lehn J M Efficient gene transfection by bisguanylated diacetylene lipid formulations. Biochemical and biophysical research communications 2001;281(2):536-43.

147. Goral V; Nelen M I; Eliseev A V; Lehn J M Double-level ”orthogonal” dynamic combinatorial libraries on transition metal template. Proceedings of the National Academy of Sciences of the United States of America 2001;98(4):1347-52.

148. Baxter P N; Lehn J M; Baum G; Fenske D Self-assembly and structure of interconverting multinuclear inorganic arrays: a. Chemistry (Weinheim an der Bergstrasse, Germany) 2000;6(24):4510-7.

149. Baxter P N; Khoury R G; Lehn J M; Baum G; Fenske D Adaptive self-assembly: environment-induced formation and reversible switching of polynuclear metallocyclophanes. Chemistry (Weinheim an der Bergstrasse, Germany) 2000;6(22):4140-8.

150. Ziener U; Breuning E; Lehn J M; Wegelius E; Rissanen K; Baum G; Fenske D; Vaughan G Recognition-directed supramolecular assemblies of metal complexes of terpyridine derived ligands with self-complementary hydrogen bonding sites. Chemistry (Weinheim an der Bergstrasse, Germany) 2000;6(22):4132-9.

151. Gardinier K M; Khoury R G; Lehn J M Enforced helicity: efficient access to self-organized helical molecular strands by the imine route. Chemistry (Weinheim an der Bergstrasse, Germany) 2000;6(22):4124-31.

152. Berl V; Huc I; Khoury R G; Krische M J; Lehn J M Interconversion of single and double helices formed from synthetic molecular strands. Nature 2000;407(6805):720-3.

153. Ramström O; Lehn J M In situ generation and screening of a dynamic combinatorial carbohydrate library against concanavalin A. Chembiochem : a European journal of chemical biology 2000;1(1):41-8.

154. Teulade-Fichou M P; Fauquet M; Baudoin O; Vigneron J P; Lehn J M DNA double helix destabilizing properties of cyclobisintercaland compounds and competition with a single strand binding protein. Bioorganic & medicinal chemistry 2000;8(1):215-22.

155. Jourdan M; Garcia J; Lhomme J; Teulade-Fichou M P; Vigneron J P; Lehn J M Threading bis-intercalation of a macrocyclic bisacridine at abasic sites in DNA: nuclear magnetic resonance and molecular modeling study. Biochemistry 1999;38(43):14205-13.

156. Pitard B; Oudrhiri N; Vigneron J P; Hauchecorne M; Aguerre O; Toury R; Airiau M; Ramasawmy R; Scherman D; Crouzet J; Lehn J M; Lehn P Structural characteristics of supramolecular assemblies formed by guanidinium-cholesterol reagents for gene transfection. Proceedings of the National Academy of Sciences of the United States of America 1999;96(6):2621-6.

157. Eliseev A V; Lehn J M Dynamic combinatorial chemistry: evolutionary formation and screening of molecular libraries. Current topics in microbiology and immunology 1999;243():159-72.

158. Blacker A J; Teulade-Fichou M P; Vigneron J P; Fauquet M; Lehn J M Selective photocleavage of single-stranded nucleic acids by cyclobisintercaland molecules. Bioorganic & medicinal chemistry letters 1998;8(6):601-6.

159. Slama-Schwok A; Peronnet F; Hantz-Brachet E; Taillandier E; Teulade-Fichou M P; Vigneron J P; Best-Belpomme M; Lehn J M A macrocyclic bis-acridine shifts the equilibrium from duplexes towards DNA hairpins. Nucleic acids research 1997;25(13):2574-81.

160. Huc I; Lehn J M Virtual combinatorial libraries: dynamic generation of molecular and supramolecular diversity by self-assembly. Proceedings of the National Academy of Sciences of the United States of America 1997;94(6):2106-10.

161. Oudrhiri N; Vigneron J P; Peuchmaur M; Leclerc T; Lehn J M; Lehn P Gene transfer by guanidinium-cholesterol cationic lipids into airway epithelial cells in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America 1997;94(5):1651-6.

162. Vigneron J P; Oudrhiri N; Fauquet M; Vergely L; Bradley J C; Basseville M; Lehn P; Lehn J M Guanidinium-cholesterol cationic lipids: efficient vectors for the transfection of eukaryotic cells. Proceedings of the National Academy of Sciences of the United States of America 1996;93(18):9682-6.

163. Hasenknopf B; Lehn J M; Baum G; Fenske D Self-assembly of a heteroduplex helicate from two different ligand strands and Cu(II) cations. Proceedings of the National Academy of Sciences of the United States of America 1996;93(4):1397-400.

164. Frugier M; Florentz C; Hosseini M W; Lehn J M; Giegé R Synthetic polyamines stimulate in vitro transcription by T7 RNA polymerase. Nucleic acids research 1994;22(14):2784-90.

165. Lehn J M Supramolecular chemistry. Science (New York, N.Y.) 1993;260(5115):1762-3.

166. Kramer R; Lehn J M; Marquis-Rigault A Self-recognition in helicate self-assembly: spontaneous formation of helical metal complexes from mixtures of ligands and metal ions. Proceedings of the National Academy of Sciences of the United States of America 1993;90(12):5394-8.

167. Gulik-Krzywicki T; Fouquey C; Lehn J Electron microscopic study of supramolecular liquid crystalline polymers formed by molecular-recognition-directed self-assembly from complementary chiral components. Proceedings of the National Academy of Sciences of the United States of America 1993;90(1):163-7.

168. Cotrait M; Kreissler M; Hoflack J; Lehn J M; Maigret B Computational simulations of the conformational behaviour of the adhesive proteins RGDS fragment. Journal of computer-aided molecular design 1992;6(2):113-30.

169. Gaucheron F; Malinge J M; Blacker A J; Lehn J M; Leng M Possible catalytic activity of DNA in the reaction between the antitumor drug cis-diamminedichloroplatinum(II) and the intercalator N-methyl-2,7-diazapyrenium. Proceedings of the National Academy of Sciences of the United States of America 1991;88(9):3516-9.

170. Slama-Schwok A; Lehn J M Interaction of porphyrin-containing macrotetracyclic receptor molecule with single-stranded and double-stranded polynucleotides. A photophysical study. Biochemistry 1990;29(34):7895-903.

171. Koert U; Harding M M; Lehn J M DNH deoxyribonucleohelicates: self assembly of oligonucleosidic double-helical metal complexes. Nature 1990;346(6282):339-42.

172. Malinge J M; Sip M; Blacker A J; Lehn J M; Leng M Formation of a DNA monofunctional cis-platinum adduct cross-linking the intercalating drug N-methyl-2,7-diazapyrenium. Nucleic acids research 1990;18(13):3887-91.

173. Slama-Schwok A; Rougée M; Ibanez V; Geacintov N E; Montenay-Garestier T; Lehn J M; Hélène C Interactions of the dimethyldiazaperopyrenium dication with nucleic acids. 2. Binding to double-stranded polynucleotides. Biochemistry 1989;28(8):3234-42.

174. Slama-Schwok A; Jazwinski J; Béré A; Montenay-Garestier T; Rougée M; Hélène C; Lehn J M Interactions of the dimethyldiazaperopyrenium dication with nucleic acids. 1. Binding to nucleic acid components and to single-stranded polynucleotides and photocleavage of single-stranded oligonucleotides. Biochemistry 1989;28(8):3227-34.

175. Lehn J M; Rigault A; Siegel J; Harrowfield J; Chevrier B; Moras D Spontaneous assembly of double-stranded helicates from oligobipyridine ligands and copper(I) cations: structure of an inorganic double helix. Proceedings of the National Academy of Sciences of the United States of America 1987;84(9):2565-9.

176. Castaing M; Lehn J M Efficiency, Na+/K+ selectivity and temperature dependence of ion transport through lipid membranes by (221)C10-cryptand, an ionizable mobile carrier. The Journal of membrane biology 1987;97(2):79-95.

177. Arrhenius T S; Blanchard-Desce M; Dvolaitzky M; Lehn J M; Malthete J Molecular devices: Caroviologens as an approach to molecular wires-synthesis and incorporation into vesicle membranes. Proceedings of the National Academy of Sciences of the United States of America 1986;83(15):5355-9.

178. Castaing M; Morel F; Lehn J M Transport of alkali cations through thin lipid membranes by (222)C10-cryptand, an ionizable mobile carrier. The Journal of membrane biology 1986;89(3):251-67.

179. Oriol-Audit C; Hosseini M W; Lehn J M ’Superpolyamines’. Macrocyclic polyamines induce highly efficient actin polymerization. European journal of biochemistry / FEBS 1985;151(3):557-9.

180. Thomas C; Sauterey C; Castaing M; Gary-Bobo C M; Lehn J M; Plumere P Cation permeability induced by two 15-O5 macrocyclic polyether carriers in phospholipidic large unilamellar vesicles. Biochemical and biophysical research communications 1983;116(3):981-7.

181. Hriciga A; Lehn J M pH regulation of divalent/monovalent Ca/K cation transport selectivity by a macrocyclic carrier molecule. Proceedings of the National Academy of Sciences of the United States of America 1983;80(20):6426-8.

182. Behr J P; Lehn J M; Dock A C; Moras D Crystal structure of a polyfunctional macrocyclic K+ complex provides a solid-state model of a K+ channel. Nature 1982;295(5849):526-7.

183. Lehn J M; Ziessel R Photochemical generation of carbon monoxide and hydrogen by reduction of carbon dioxide and water under visible light irradiation. Proceedings of the National Academy of Sciences of the United States of America 1982;79(2):701-4.

184. Grimaldi J J; Boileau S; Lehn J Light-driven, carrier-mediated electron transfer across artificial membranes. Nature 1977;265(5591):229-30.

185. Lehn J M Design of synthetic receptor and carrier molecules for the Li+ cation. Neurosciences Research Program bulletin 1976;14(2):133-7.

186. Lehn J M; Wipff G Stereoelectronic properties and reactivity of the tetrahedral intermediate in amide hydrolysis. Nonempirical study of aminodihydroxymethane and relation to enzyme catalysis. Journal of the American Chemical Society 1974;96(12):4048-50.

187. Behr J P; Lehn J M Transport of amino acids through organic liquid membranes. Journal of the American Chemical Society 1973;95(18):6108-10.

188. Behr J P; Lehn J M The binding of divalent cations by purified gangliosides. FEBS letters 1973;31(3):297-300.

189. Behr J P; Lehn J M Molecular dynamics of acetylcholine and of choline. Biochemical and biophysical research communications 1972;49(6):1573-9.



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    Professor of Chemistry
    University Louis Pasteur, Strasbourg