Barry James Marshall

Barry Marshall is an Australian physician Professor of Clinical Microbiology at the University of Western Australia.

He won the Nobel Prize for Physiology or Medicine in 2005 for his discovery that the H. pylori bacteria is the cause of many peptic ulcers and gastric cancer.  His theory was for a long time rejected by the medical community who insisted that bacteria could not survive in the acidic environment of the stomach.  After failed experiments on pigs, Marshall drank a petri dish of the H. pylori bacteria and 5 days later developed gastritis.

His blog is at : http://barryjmarshall.blogspot.com/ where he shares his thoughts and findings.

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Biologist BIOLOGIST (Clinical Microbiologist)
Barry Barry Marshall
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1.    1994 Warren Alpert Prize (shared with J.R. Warren)
2.    1995 Australian Medical Association Award (shared with J.R. Warren)
3.    1995 Albert Lasker Award 1996 Gairdner Award
4.    1997 Paul Ehrlich Prize (shared with J.R. Warren)
5.    1998 DR AH Heineken Prize for Medicine, Amsterdam
6.    1998 Florey Medal, Canberra
7.    1998 Buchanan Medal, Royal Society
8.    1999 Benjamin Franklin Medal for Life Sciences, Philadelphia
9.    2002 Keio Medical Science Prize
10.    2003 Australian Centenary Medal
11.    2005 Karolinska Institute in Stockholm
12.    2005 Nobel Prize in Physiology or Medicine

A3: Book Edited

Marshall, B.J. 2002, Helicobacter pioneers: Firsthand accounts from the scientists who discovered helicobacters, 1892-1982Blackwell Science Asia Pty Ltd, Melbourne, Australia 

B1: Book Chapter (Commercial)

Fukuda, Y., Shimoyama, T., Marshall, B.J. 2002, Kasai, Kobayashi and Koch’s postulates in the history of Helicobacter pylori in Helicobacter pioneers: Firsthand accounts from the scientists who discovered helicobacters, 1892-1982, Blackwell Science , Melbourne, Australia 

Peterson, W.L., Harford, W., Marshall, B.J. 2002, The Dallas experience with acute Helicobacter pylori infection in Helicobacter pioneers: Firsthand accounts from the scientists who discovered helicobacters, 1892-1982, Blackwell Science , Melbourne, Australia 

Marshall, B.J. 2002, The discovery that Helicobacter pylori, a spiral bacterium, caused peptic ulcer disease in Helicobacter pioneers: Firsthand accounts from the scientists who discovered helicobacters, 1892-1982, Blackwell Science , Melbourne, Australia 

Marshall, B.J. 2001, One hundred years of discovery and rediscovery of Helicobacter pylori and its association with peptic ulcer disease in Helicobacter pylori: Physiology and Genetics, ASM Press , Washington 

C1: Journal Article (Schol Refereed Journal)

MOODLEY, Y., LINZ, B., YAMAOKA, Y., WINDSOR, H.M., BREUREC, S., WU, J-Y., MAADY, A., BERNHOFT, S., THIBERGE, J-M., PHUANUKOONON, S., JOBB, G., SIBA, P., GRAHAM, D.Y., MARSHALL, B.J., ACHTMAN, M. 2009, ’The Peopling of the Pacific from a Bacterial Perspective’, Science, 323, pp. 527-530. 

DUMRESE, C., SLOMIANKA, L., ZIEGLER, U., CHOI, S.S., KALIA, A., FULURIJA, A., LU, W., BERG, D.E., BENGHEZAL, M., MARSHALL, B.J., MITTL, P.R.E. 2009, ’The secreted Helicobacter cysteine-rich protein A causes adherence of human monocytes and differentiation into a macrophage-like phenotype’, FEBS Letters, 583, pp. 1637-1643. 

Stenstrom, B, Mendis, A, Marshall, B 2008, ’Helicobacter pylori – The latest in diagnosis and treatment’, AUSTRALIAN FAMILY PHYSICIAN, 37, pp. 608-612. 

Marshall, B.J., Schoep, T.D. 2007, ’Helicobacter pylori as a Vaccine Delivery System’, Helicobacter (Oxford), 12, SUPPL. 2, pp. 75-79. 

Suzuki, H., Hibi, T., Marshall, B.J. 2007, ’Helicobacter pylori: present status and future prospects in Japan’, Journal of Gastroenterology, 42, 1, pp. 1-15. 

Windsor, H.M., Abioye-Kuteyi, E.A., Leber, J.M., Morrow, S.D., Bulsara, M.K., Marshall, B.J. 2005, ’Prevalence of  Helicobacter pylori in Indigenous West Australians: comparison between urban and remote rural populations’, Medical Journal of Australia, 182, 5, pp. 210-213. 

Lloyd, A.L., Marshall, B.J., Mee, B.J. 2005, ’Identifying cloned Helicobacter pylori promoters by primer extension using a FAM-labelled primer and GeneScan® analysis’, Journal of Microbiological Methods, 60, pp. 291-298. 

Marshall, B.J., Windsor, H.M. 2005, ’The relation of Helicobacter pylori to gastric adenocarcinoma and lymphoma: pathophysiology, epidemiology, screening, clinical presentation, treatment, and prevention’, Medical Clinics of North America, 89, 2, pp. 313-344. 

Guttner, Y., Windsor, H.M., Viiala, C.H., Dusci, L., Marshall, B.J. 2003, ’Nitazoxanide in Treatment of Helicobacter pylori: a Clinical and In Vitro Study’, Antimicrobial Agents and Chemotherapy, 47, 12, pp. 3780-3783. 

Guttner, Y., Windsor, H.M., Viiala, C.H., Marshall, B.J. 2003, ’Human recombinant lactoferrin is ineffective in the treatment of human Helicobacter pylori infection’, Alimentary Pharmacology and Therapeutics, 17, pp. 125-129. 

Marshall, B.J. 2002, ’Helicobacter pylori: 20 years on’, Clinical Medicine, 2, pp. 147-152. 

Viiala, C.H., Windsor, H.M., Forbes, G.M., Chairman, S.O., Marshall, B.J., Mollison, L.C. 2002, ’Helicobacter Pylori – Evaluation of a new formulation CLOtest’, Journal of Gastroenterology and Hepatology, 17, pp. 127-130. 

Ho, G.Y., Windsor, H.M., Snowball, B., Marshall, B.J. 2001, ’Helicobacter pylori is not the cause of sudden infant death syndrome (SIDS)’, American Journal of Gastroenterology, 96, pp. 3288-3294. 

Samuels, A.L., Windsor, H.M., Ho, G.Y., Goodwin, L.D., Marshall, B.J. 2000, ’Culture of Helicobacter pylori from a gastric string may be an alternative to endoscopic biopsy’, Journal of Clinical Microbiology, 38, pp. 2438-2439. 

Windsor, H.M., Ho, G.Y., Marshall, B.J. 1999, ’Successful Recovery of H. pylori from Rapid Urease Tests (CLO Tests)’, The American Journal of Gastroenterology, 94, 11, pp. 3181-3183. 

C12: Journal Article (Review Article)

Talley, N.J., Vakil, N., Delaney, B., Marshall, B.J., Bytzer, P., Engstrand, L., de Boer, W., Jones, R., Malfertheiner, P., Agreus, L. 2004, ’Management Issues in Dyspepsia: Curent Consensus and Controversies’, Scandinavian Journal of Gastroenterology, 39, 10, pp. 913-918. 

Marshall, B.J. 2002, ’Commentary: Helicobacter as the ’environmental factor’ in Susser and Stein’s cohort theory of peptic ulcer disease’, International Journal of Epidemiology, 31, pp. 21-22. 

C2: Other Contribution to Refereed Journal

Stenstrom, B., Mendis, A., Marshall, B.J. 2008, ’Helicobacter pylori’, Australian Family Physician, 37, 8, pp. 608-612. 

Windsor, H.M., Abioye-Kuteyi, E.A., Marshall, B.J. 2005, ’Methodology and Transport Medium for Collection of Helicobacter pylori on a String Test in Remote Locations’, Helicobacter, 10, 6, pp. 630-634. 

Marshall, B.J. 2002, ’Gastric spirochaetes: 100 years of discovery before and after Kobayashi’, Keio Journal of Medicine, 51 Supplement 2, pp. 33-37. 

C3: Journal Article (Non Refereed)

Stenstrom, B., Mendis, A., Marshall, B.J. 2008, ’Helicobacter pylori: The latest in diagnosis and treatment’, Australian Family Physician, 37, 8, pp. N/A. 

Marshall, B.J. 2005, ’The Lasker Awards: Celebrating Scientific Discovery’, JAMA: The Journal of the American Medical Association, 294, 11, pp. 1420-1421. 

Ho, B., Marshall, B.J. 2000, ’Accurate diagnosis of Helicobacter pylori: serologic testing’, Gastroenterology Clinics of North America: Helicobacter pylori, Part II, 29, 4, pp. 853-862. 

Megraud, F., Marshall, B.J. 2000, ’How to treat Helicobacter pylori’, Gastroenterology Clinics of North America: Helicobacter pylori, Part II, 29, 4, pp. 759-773. 

Midolo, P., Marshall, B.J. 2000, ’Accurate diagnosis of Helicobacter pylori: urease tests’, Gastroenterology Clinics of North America: Helicobacter pylori, Part II, 29, 4, pp. 871-878. 

Sipponen, P., Marshall, B.J. 2000, ’Gastritis and gastric cancer: Western countries’, Gastroenterology Clinics of North America: Helicobacter pylori, Part I, 29, 3, pp. 579-592. 

C4: Journal Article (Letter Or Note)

Marshall, B 2008, ’Sequential therapy for Helicobacter pylori: A worthwhile effort for your patients’, ANNALS OF INTERNAL MEDICINE, 148, pp. 962-963. 

Viiala, C.H., Windsor, H.M., Marshall, B.J. 2005, ’Cure Rate of High Dose Omeprazole and Amoxicillin Therapy for Treatment-resistant Helicobacter pylori Infection’, Journal of Gastroenterology and Hepatology, 20, 4, pp. 663-664. 

Marshall, B.J., Bulsara, M. 2003, ’Controlled trial of cumulative behavioural effects of a common bread preservative’, Journal of Paediatrics and Child Health, 39, 7, pp. 568. 

Marshall, B.J., Ho, G.Y. 2001, ’Controls not matched’, Archives of Disease in Childhood, 84, pp. 529. 

D: Major Review

Marshall, B.J. 2005, ’Gastritis and peptic ulcer disease’, Rekel, R.E., Bope, E.T., pp. 600-605. 

Marshall, B.J. 2003, ’Helicobacter pylori: past, present and future’, Commemorative Lecture, 52, 2, pp. 80-85. 

L: Technical Report

Lockhart, J., Kerridge, I., Marshall, B.J., McCombe, P., Schofield, P., Skene, L. 2005, ’Prohibition of Human Cloning Act 2002 and Research Involving Human Embryos Act 2002’, http://www.ag.gov.au/cca, 1, pp. 1-284. 



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