Dr. Qiang Zhou

Qiang Zhou is a Professor of Biochemistry and Molecular Biology at the University of California Berkeley, whose main research interests include mechanisms and factors that control transcriptional elongation and their impact on HIV replication.

Public Rating
0 points
Academy Rating
13 points
Overall Rating
13 points
Biologist BIOLOGIST (Biochemist)
Qiang Zhou
Previous Next

Recent Findings From Dr. Qiang Zhou

Subscribe by RSS

No record yet.

No record yet.

Popular publications

  • A capping-independent function of BCDIN3 in stabilizing 7SK snRNA and facilitating the assembly of 7SK snRNP. [Y. Xue, Z. Yang, R. Chen, and Q. Zhou. Submitted]
  • A La-related protein modulates 7SK snRNP integrity to suppress P-TEFb-dependent transcriptional elongation and tumorigenesis. [N. He, N.S. Jahchan, E. Hong, M. A. Bayfield,  R. J. Maraia, K. Luo, and Q. Zhou (2008). Mol. Cell29, 588-599]
  • PP2B and PP1α cooperatively disrupt 7SK snRNP to release P-TEFb for transcription in response to Ca2+ signaling. [C. Chen, M. Liu, H. Li, Y. Xue, W.N. Ramey, N. He, N. Ai, H. Luo, Y. Zhu, N. Zhou, and Q. Zhou (2008) Genes & Dev.22, 1356-1368]
  • Brd4 recruits P-TEFb to chromosomes at late mitosis to promote G1 gene expression and cell cycle progression. [Z. Yang, N. He, and Q. Zhou (2008) Mol. Cell. Biol. 28, 967-976]
  • Tat competes with HEXIM1 to increase the active pool of P-TEFb for HIV-1 transcription. [M. Barboric, J. H. N. Yik, N. Czudnochowski, Z. Yang, R. Chen, X. Contreras, M. Geyer, B. M. Peterlin, and Q. Zhou (2007) Nuc. Acids Res. 35, 2003-2012]
  • Modulation of a P-TEFb functional equilibrium for the global control of cell growth and differentiation. [N. He, A. C. Pezda and Q. Zhou (2006) Mol. Cell. Biol. 26, 7068-7076]
  • The Yin and Yang of P-TEFb regulation: Implications for HIV gene expression and the global control of cell growth and differentiation. [J. H. N. Yik and Q. Zhou (2006)Microbiol. Mol Biol. Rev. 70, 646-659]
  • Recruitment of P-TEFb for stimulation of transcriptional elongation by bromodomain protein Brd4. [Z. Yang, J. H. N. Yik, R. Chen, M. K. Jang, K. Ozato and Q. Zhou (2005) Mol. Cell 19, 535-545]
  • A human immunodeficiency virus type 1 Tat-like arginine-rich RNA-binding domain is essential for HEXIM1 to inhibit RNA polymerase II transcription through 7SK snRNA-mediated inactivation of P-TEFb. [J. H. N. Yik, R. Chen, A. C. Pezda, C. S. Samford and Q. Zhou (2004) Mol. Cell. Biol. 24, 5094-5105]
  • Phosphorylated P-TEFb is tagged for inhibition through association with 7SK snRNA. [R. Chen, Z. Yang and Q. Zhou (2004) J. Biol. Chem. 279, 4153-4160]
  • Inhibition of P-TEFb (CDK9/cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA. [J. H. N. Yik, R. Chen, R. Nishimura, J. L. Jennings, A. J. Link and Q. Zhou (2003) Mol. Cell 12, 971-982]
  • The 7SK small nuclear RNA inhibits the Cdk9/cyclin T1 kinase to control transcription. [Z. Yang, Q. Zhu, K. Luo, and Q. Zhou (2001) Nature 414, 317-322]
  • Stimulatory effect of splicing factors on transcriptional elongation. [Y. Fong and Q. Zhou (2001) Nature 414, 929-933]

Photos of Dr. Qiang Zhou

Comments are closed.

  • Postings

    Professor of Biochemistry and Molecular Biology
    University of California