1991 Feldberg Prize for Medical Research (UK/Germany)
1992 Louis Jeantet Prize for Medicine in Europe (Switzerland)
1992 Gairdner Foundation International Award (Canada)
1993 Royal Society Wellcome Medal (UK)
1993 Jimenez Diaz Memorial Award and Medal (Spain)
1993 Rosenstiel Award and Medal for Distinguished Work in Basic Medical Sciences (USA)
1994 Purkyne Medal, Czech Academy of Science (Czech Republic)
1995 Pezcoller Award for Oncology Research (Italy)
1995 Royal Society Royal Medal (UK)
1996 Dr. Josef Steiner Prize (Switzerland)
1996 Dr. H. P. Heineken Prize for Biochemistry & Biophysics (The Netherlands)
1997 General Motors Cancer Research Foundation Alfred P. Sloan Jr. Prize & Medal (USA)
1998 Berkan Judd Award (USA)
1998 Albert Lasker Award (USA)
2001 Nobel Prize in Physiology or Medicine
Nurse, P; Hayles, J The cell in an era of systems biology. Cell 2011;144(6):850-4.
Coudreuse, D; Nurse, P Driving the cell cycle with a minimal CDK control network. Nature 2010;468(7327):1074-9.
Zhurinsky, J; Leonhard, K; Watt, S; Marguerat, S; Bähler, J; Nurse, P A coordinated global control over cellular transcription. Current biology : CB 2010;20(22):2010-5.
Kiang, L; Heichinger, C; Watt, S; Bähler, J; Nurse, P Specific replication origins promote DNA amplification in fission yeast. Journal of cell science 2010;123(Pt 18):3047-51.
Moseley, JB; Nurse, P Cell division intersects with cell geometry. Cell 2010;142(2):184-8.
Castagnetti, S; Oliferenko, S; Nurse, P Fission yeast cells undergo nuclear division in the absence of spindle microtubules. PLoS biology 2010;8(10):e1000512.
Kiang, L; Heichinger, C; Watt, S; Bähler, J; Nurse, P Cyclin-dependent kinase inhibits reinitiation of a normal S-phase program during G2 in fission yeast. Molecular and cellular biology 2009;29(15):4025-32.
Riveline, D; Nurse, P ’Injecting’ yeast. Nature methods 2009;6(7):513-4.
Moseley, JB; Mayeux, A; Paoletti, A; Nurse, P A spatial gradient coordinates cell size and mitotic entry in fission yeast. Nature 2009;459(7248):857-60.
Wu, PY; Nurse, P Establishing the program of origin firing during S phase in fission Yeast. Cell 2009;136(5):852-64.
Moseley, JB; Nurse, P Cdk1 and cell morphology: connections and directions. Current opinion in cell biology 2009;21(1):82-8.
Lygeros, J; Koutroumpas, K; Dimopoulos, S; Legouras, I; Kouretas, P; Heichinger, C; Nurse, P; Lygerou, Z Stochastic hybrid modeling of DNA replication across a complete genome. Proceedings of the National Academy of Sciences of the United States of America 2008;105(34):12295-300.
Nurse, P Life, logic and information. Nature 2008;454(7203):424-6.
Daga, RR; Nurse, P Interphase microtubule bundles use global cell shape to guide spindle alignment in fission yeast. Journal of cell science 2008;121(Pt 12):1973-80.
Greene, B; Nurse, P Science on the streets of the Big Apple. Cell 2008;133(5):757-8.
Neumann, FR; Nurse, P Nuclear size control in fission yeast. The Journal of cell biology 2007;179(4):593-600.
Petersen, J; Nurse, P TOR signalling regulates mitotic commitment through the stress MAP kinase pathway and the Polo and Cdc2 kinases. Nature cell biology 2007;9(11):1263-72.
Castagnetti, S; Novák, B; Nurse, P Microtubules offset growth site from the cell centre in fission yeast. Journal of cell science 2007;120(Pt 13):2205-13.
Hermand, D; Nurse, P Cdc18 enforces long-term maintenance of the S phase checkpoint by anchoring the Rad3-Rad26 complex to chromatin. Molecular cell 2007;26(4):553-63.
Fersht, N; Hermand, D; Hayles, J; Nurse, P Cdc18/CDC6 activates the Rad3-dependent checkpoint in the fission yeast. Nucleic acids research 2007;35(16):5323-37.
Carazo-Salas, R; Nurse, P Sorting out interphase microtubules. Molecular systems biology 2007;3():95.
Heichinger, C; Penkett, CJ; Bähler, J; Nurse, P Genome-wide characterization of fission yeast DNA replication origins. The EMBO journal 2006;25(21):5171-9.
Carazo-Salas, RE; Nurse, P Self-organization of interphase microtubule arrays in fission yeast. Nature cell biology 2006;8(10):1102-7.
Nurse, P US biomedical research under siege. Cell 2006;124(1):9-12.
Malapeira, J; Moldón, A; Hidalgo, E; Smith, GR; Nurse, P; Ayté, J A meiosis-specific cyclin regulated by splicing is required for proper progression through meiosis. Molecular and cellular biology 2005;25(15):6330-7.
Carazo-Salas, RE; Antony, C; Nurse, P The kinesin Klp2 mediates polarization of interphase microtubules in fission yeast. Science (New York, N.Y.) 2005;309(5732):297-300.
Castagnetti, S; Behrens, R; Nurse, P End4/Sla2 is involved in establishment of a new growth zone in Schizosaccharomyces pombe. Journal of cell science 2005;118(Pt 9):1843-50.
Pardo, M; Nurse, P The nuclear rim protein Amo1 is required for proper microtubule cytoskeleton organisation in fission yeast. Journal of cell science 2005;118(Pt 8):1705-14.
Leonhard, K; Nurse, P Ste20/GCK kinase Nak1/Orb3 polarizes the actin cytoskeleton in fission yeast during the cell cycle. Journal of cell science 2005;118(Pt 5):1033-44.
Nurse, P Wee beasties. Nature 2004;432(7017):557.
Niccoli, T; Yamashita, A; Nurse, P; Yamamoto, M The p150-Glued Ssm4p regulates microtubular dynamics and nuclear movement in fission yeast. Journal of cell science 2004;117(Pt 23):5543-56.
Xouri, G; Lygerou, Z; Nishitani, H; Pachnis, V; Nurse, P; Taraviras, S Cdt1 and geminin are down-regulated upon cell cycle exit and are over-expressed in cancer-derived cell lines. European journal of biochemistry / FEBS 2004;271(16):3368-78.
Rustici, G; Mata, J; Kivinen, K; Lió, P; Penkett, CJ; Burns, G; Hayles, J; Brazma, A; Nurse, P; Bähler, J Periodic gene expression program of the fission yeast cell cycle. Nature genetics 2004;36(8):809-17.
Busch, KE; Hayles, J; Nurse, P; Brunner, D Tea2p kinesin is involved in spatial microtubule organization by transporting tip1p on microtubules. Developmental cell 2004;6(6):831-43.
Niccoli, T; Arellano, M; Nurse, P Role of Tea1p, Tea3p and Pom1p in the determination of cell ends in Schizosaccharomyces pombe. Yeast (Chichester, England) 2003;20(16):1349-58.
Drewes, G; Nurse, P The protein kinase kin1, the fission yeast orthologue of mammalian MARK/PAR-1, localises to new cell ends after mitosis and is important for bipolar growth. FEBS letters 2003;554(1-2):45-9.
Nurse, P; Pattison, J; Radda, G; O’Toole, L Cancer research: joint planning for the future. Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2003;14(11):1593-4.
Nurse, P The great ideas of biology. Clinical medicine (London, England) 2003;3(6):560-8.
Browning, H; Hackney, DD; Nurse, P Targeted movement of cell end factors in fission yeast. Nature cell biology 2003;5(9):812-8.
Nurse, P Systems biology: understanding cells. Nature 2003;424(6951):883.
Pardo, M; Nurse, P Equatorial retention of the contractile actin ring by microtubules during cytokinesis. Science (New York, N.Y.) 2003;300(5625):1569-74.
Yamaguchi, S; Decottignies, A; Nurse, P Function of Cdc2p-dependent Bub1p phosphorylation and Bub1p kinase activity in the mitotic and meiotic spindle checkpoint. The EMBO journal 2003;22(5):1075-87.
Decottignies, A; Sanchez-Perez, I; Nurse, P Schizosaccharomyces pombe essential genes: a pilot study. Genome research 2003;13(3):399-406.
O’Toole, L; Nurse, P; Radda, G An analysis of cancer research funding in the UK. Nature reviews. Cancer 2003;3(2):139-43.
Wuarin, J; Buck, V; Nurse, P; Millar, JB Stable association of mitotic cyclin B/Cdc2 to replication origins prevents endoreduplication. Cell 2002;111(3):419-31.
Nurse, PM Nobel Lecture. Cyclin dependent kinases and cell cycle control. Bioscience reports 2002;22(5-6):487-99.
Nurse, P Cyclin dependent kinases and cell cycle control (nobel lecture). Chembiochem : a European journal of chemical biology 2002;3(7):596-603.
Zarzov, P; Decottignies, A; Baldacci, G; Nurse, P G(1)/S CDK is inhibited to restrain mitotic onset when DNA replication is blocked in fission yeast. The EMBO journal 2002;21(13):3370-6.
Borgne, A; Murakami, H; Ayté, J; Nurse, P The G1/S cyclin Cig2p during meiosis in fission yeast. Molecular biology of the cell 2002;13(6):2080-90.
Behrens, R; Nurse, P Roles of fission yeast tea1p in the localization of polarity factors and in organizing the microtubular cytoskeleton. The Journal of cell biology 2002;157(5):783-93.
Murakami, H; Yanow, SK; Griffiths, D; Nakanishi, M; Nurse, P Maintenance of replication forks and the S-phase checkpoint by Cdc18p and Orp1p. Nature cell biology 2002;4(5):384-8.
Arellano, M; Niccoli, T; Nurse, P Tea3p is a cell end marker activating polarized growth in Schizosaccharomyces pombe. Current biology : CB 2002;12(9):751-6.
Niccoli, T; Nurse, P Different mechanisms of cell polarisation in vegetative and shmooing growth in fission yeast. Journal of cell science 2002;115(Pt 8):1651-62.
Nurse, P The Nobel Prize and beyond: an interview with Sir Paul Nurse. Interview by Susan R. Owens. EMBO reports 2002;3(3):204-6.
Wood, V; Gwilliam, R; Rajandream, MA; Lyne, M; Lyne, R; Stewart, A; Sgouros, J; Peat, N; Hayles, J; Baker, S; Basham, D; Bowman, S; Brooks, K; Brown, D; Brown, S; Chillingworth, T; Churcher, C; Collins, M; Connor, R; Cronin, A; Davis, P; Feltwell, T; Fraser, A; Gentles, S; Goble, A; Hamlin, N; Harris, D; Hidalgo, J; Hodgson, G; Holroyd, S; Hornsby, T; Howarth, S; Huckle, EJ; Hunt, S; Jagels, K; James, K; Jones, L; Jones, M; Leather, S; McDonald, S; McLean, J; Mooney, P; Moule, S; Mungall, K; Murphy, L; Niblett, D; Odell, C; Oliver, K; O’Neil, S; Pearson, D; Quail, MA; Rabbinowitsch, E; Rutherford, K; Rutter, S; Saunders, D; Seeger, K; Sharp, S; Skelton, J; Simmonds, M; Squares, R; Squares, S; Stevens, K; Taylor, K; Taylor, RG; Tivey, A; Walsh, S; Warren, T; Whitehead, S; Woodward, J; Volckaert, G; Aert, R; Robben, J; Grymonprez, B; Weltjens, I; Vanstreels, E; Rieger, M; Schäfer, M; Müller-Auer, S; Gabel, C; Fuchs, M; Düsterhöft, A; Fritzc, C; Holzer, E; Moestl, D; Hilbert, H; Borzym, K; Langer, I; Beck, A; Lehrach, H; Reinhardt, R; Pohl, TM; Eger, P; Zimmermann, W; Wedler, H; Wambutt, R; Purnelle, B; Goffeau, A; Cadieu, E; Dréano, S; Gloux, S; Lelaure, V; Mottier, S; Galibert, F; Aves, SJ; Xiang, Z; Hunt, C; Moore, K; Hurst, SM; Lucas, M; Rochet, M; Gaillardin, C; Tallada, VA; Garzon, A; Thode, G; Daga, RR; Cruzado, L; Jimenez, J; Sánchez, M; del Rey, F; Benito, J; Domínguez, A; Revuelta, JL; Moreno, S; Armstrong, J; Forsburg, SL; Cerutti, L; Lowe, T; McCombie, WR; Paulsen, I; Potashkin, J; Shpakovski, GV; Ussery, D; Barrell, BG; Nurse, P; Cerrutti, L The genome sequence of Schizosaccharomyces pombe. Nature 2002;415(6874):871-80.
Ayté, J; Schweitzer, C; Zarzov, P; Nurse, P; DeCaprio, JA Feedback regulation of the MBF transcription factor by cyclin Cig2. Nature cell biology 2001;3(12):1043-50.
Nurse, P Interview: Sir Paul Nurse, PhD, Nobel Prize for Medicine Winner. MedGenMed : Medscape general medicine 2001;3(4):4.
Yanow, SK; Lygerou, Z; Nurse, P Expression of Cdc18/Cdc6 and Cdt1 during G2 phase induces initiation of DNA replication. The EMBO journal 2001;20(17):4648-56.
Hayles, J; Nurse, P A journey into space. Nature reviews. Molecular cell biology 2001;2(9):647-56.
Decottignies, A; Zarzov, P; Nurse, P In vivo localisation of fission yeast cyclin-dependent kinase cdc2p and cyclin B cdc13p during mitosis and meiosis. Journal of cell science 2001;114(Pt 14):2627-40.
Murakami, H; Nurse, P Regulation of premeiotic S phase and recombination-related double-strand DNA breaks during meiosis in fission yeast. Nature genetics 2001;28(3):290-3.
Bähler, J; Nurse, P Fission yeast Pom1p kinase activity is cell cycle regulated and essential for cellular symmetry during growth and division. The EMBO journal 2001;20(5):1064-73.
Watanabe, Y; Yokobayashi, S; Yamamoto, M; Nurse, P Pre-meiotic S phase is linked to reductional chromosome segregation and recombination. Nature 2001;409(6818):359-63.
Griffiths, DJ; Liu, VF; Nurse, P; Wang, TS Role of fission yeast primase catalytic subunit in the replication checkpoint. Molecular biology of the cell 2001;12(1):115-28.
Lygerou, Z; Nurse, P Cell cycle. License withheld–geminin blocks DNA replication. Science (New York, N.Y.) 2000;290(5500):2271-3.
Behrens, R; Hayles, J; Nurse, P Fission yeast retrotransposon Tf1 integration is targeted to 5’ ends of open reading frames. Nucleic acids research 2000;28(23):4709-16.
Borgne, A; Nurse, P The Spd1p S phase inhibitor can activate the DNA replication checkpoint pathway in fission yeast. Journal of cell science 2000;113 Pt 23():4341-50.
Browning, H; Hayles, J; Mata, J; Aveline, L; Nurse, P; McIntosh, JR Tea2p is a kinesin-like protein required to generate polarized growth in fission yeast. The Journal of cell biology 2000;151(1):15-28.
Nurse, P The incredible life and times of biological cells. Science (New York, N.Y.) 2000;289(5485):1711-6.
Brunner, D; Nurse, P CLIP170-like tip1p spatially organizes microtubular dynamics in fission yeast. Cell 2000;102(5):695-704.
Yamaguchi, S; Okayama, H; Nurse, P Fission yeast Fizzy-related protein srw1p is a G(1)-specific promoter of mitotic cyclin B degradation. The EMBO journal 2000;19(15):3968-77.
Brunner, D; Nurse, P New concepts in fission yeast morphogenesis. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2000;355(1399):873-7.
Murakami, H; Nurse, P DNA replication and damage checkpoints and meiotic cell cycle controls in the fission and budding yeasts. The Biochemical journal 2000;349(Pt 1):1-12.
Nishitani, H; Lygerou, Z; Nishimoto, T; Nurse, P The Cdt1 protein is required to license DNA for replication in fission yeast. Nature 2000;404(6778):625-8.
Grallert, B; Kearsey, SE; Lenhard, M; Carlson, CR; Nurse, P; Boye, E; Labib, K A fission yeast general translation factor reveals links between protein synthesis and cell cycle controls. Journal of cell science 2000;113 ( Pt 8)():1447-58.
Griffiths, D; Uchiyama, M; Nurse, P; Wang, TS A novel mutant allele of the chromatin-bound fission yeast checkpoint protein Rad17 separates the DNA structure checkpoints. Journal of cell science 2000;113 ( Pt 6)():1075-88.
Nurse, P A long twentieth century of the cell cycle and beyond. Cell 2000;100(1):71-8.
Lygerou, Z; Nurse, P Controlling S-phase onset in fission yeast. Cold Spring Harbor symposia on quantitative biology 2000;65():323-32.
Sawin, KE; Hajibagheri, MA; Nurse, P Mis-specification of cortical identity in a fission yeast PAK mutant. Current biology : CB 1999;9(22):1335-8.
Lygerou, Z; Nurse, P The fission yeast origin recognition complex is constitutively associated with chromatin and is differentially modified through the cell cycle. Journal of cell science 1999;112 ( Pt 21)():3703-12.
Murakami, H; Nurse, P Meiotic DNA replication checkpoint control in fission yeast. Genes & development 1999;13(19):2581-93.
Watanabe, Y; Nurse, P Cohesin Rec8 is required for reductional chromosome segregation at meiosis. Nature 1999;400(6743):461-4.
Patterson, TE; Albrecht, EB; Nurse, P; Sazer, S; Stark, GR Effects of genome position and the DNA damage checkpoint on the structure and frequency of sod2 gene amplification in fission yeast. Molecular biology of the cell 1999;10(7):2199-208.
Nurse, P Felix Hoppe-Seyler Lecture 1999. Cyclin dependent kinases and regulation of the fission yeast cell cycle. Biological chemistry 1999;380(7-8):729-33.
Nurse, P The Imperial Cancer Research Fund–cancer research for the future. Nature medicine 1998;4(11):1224-7.
Nurse, P Yoshio Masui and cell cycle control, past, present and future. Biology of the cell / under the auspices of the European Cell Biology Organization 1998;90(6-7):447-52.
Nurse, P; Masui, Y; Hartwell, L Understanding the cell cycle. Nature medicine 1998;4(10):1103-6.
West, RR; Vaisberg, EV; Ding, R; Nurse, P; McIntosh, JR cut11(+): A gene required for cell cycle-dependent spindle pole body anchoring in the nuclear envelope and bipolar spindle formation in Schizosaccharomyces pombe. Molecular biology of the cell 1998;9(10):2839-55.
Baum, B; Nishitani, H; Yanow, S; Nurse, P Cdc18 transcription and proteolysis couple S phase to passage through mitosis. The EMBO journal 1998;17(19):5689-98.
Greenwood, E; Nishitani, H; Nurse, P Cdc18p can block mitosis by two independent mechanisms. Journal of cell science 1998;111 ( Pt 20)():3101-8.
Sawin, KE; Nurse, P Regulation of cell polarity by microtubules in fission yeast. The Journal of cell biology 1998;142(2):457-71.
Verde, F; Wiley, DJ; Nurse, P Fission yeast orb6, a ser/thr protein kinase related to mammalian rho kinase and myotonic dystrophy kinase, is required for maintenance of cell polarity and coordinates cell morphogenesis with the cell cycle. Proceedings of the National Academy of Sciences of the United States of America 1998;95(13):7526-31.
Stern, B; Nurse, P Cyclin B proteolysis and the cyclin-dependent kinase inhibitor rum1p are required for pheromone-induced G1 arrest in fission yeast. Molecular biology of the cell 1998;9(6):1309-21.
Cooper, JP; Watanabe, Y; Nurse, P Fission yeast Taz1 protein is required for meiotic telomere clustering and recombination. Nature 1998;392(6678):828-31.
Mata, J; Nurse, P Discovering the poles in yeast. Trends in cell biology 1998;8(4):163-7.
Nurse, P Reductionism and explanation in cell biology. Novartis Foundation symposium 1998;213():93-101; discussion 102-5.
Nurse, P Checkpoint pathways come of age. Cell 1997;91(7):865-7.
Nurse, P Imperial Cancer Research Fund and the Lancet. Lancet 1997;350(9091):1626; author reply 1627.
D’Urso, G; Nurse, P Schizosaccharomyces pombe cdc20+ encodes DNA polymerase epsilon and is required for chromosomal replication but not for the S phase checkpoint. Proceedings of the National Academy of Sciences of the United States of America 1997;94(23):12491-6.
Baum, B; Wuarin, J; Nurse, P Control of S-phase periodic transcription in the fission yeast mitotic cycle. The EMBO journal 1997;16(15):4676-88.
Correa-Bordes, J; Gulli, MP; Nurse, P p25rum1 promotes proteolysis of the mitotic B-cyclin p56cdc13 during G1 of the fission yeast cell cycle. The EMBO journal 1997;16(15):4657-64.
Grallert, B; Nurse, P An approach to identify functional homologues and suppressors of genes in fission yeast. Current genetics 1997;32(1):27-31.
Mata, J; Nurse, P tea1 and the microtubular cytoskeleton are important for generating global spatial order within the fission yeast cell. Cell 1997;89(6):939-49.
Nurse, P Reductionism. The ends of understanding. Nature 1997;387(6634):657.
Nurse, P Regulation of the eukaryotic cell cycle. European journal of cancer (Oxford, England : 1990) 1997;33(7):1002-4.
Nurse, P The Josef Steiner Lecture: CDKs and cell-cycle control in fission yeast: relevance to other eukaryotes and cancer. International journal of cancer. Journal international du cancer 1997;71(5):707-8.
Chang, F; Drubin, D; Nurse, P cdc12p, a protein required for cytokinesis in fission yeast, is a component of the cell division ring and interacts with profilin. The Journal of cell biology 1997;137(1):169-82.
O’Connell, MJ; Raleigh, JM; Verkade, HM; Nurse, P Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation. The EMBO journal 1997;16(3):545-54.
Stern, B; Nurse, P Fission yeast pheromone blocks S-phase by inhibiting the G1 cyclin B-p34cdc2 kinase. The EMBO journal 1997;16(3):534-44.
Nishitani, H; Nurse, P The cdc18 protein initiates DNA replication in fission yeast. Progress in cell cycle research 1997;3():135-42.
Sawin, KE; Nurse, P Identification of fission yeast nuclear markers using random polypeptide fusions with green fluorescent protein. Proceedings of the National Academy of Sciences of the United States of America 1996;93(26):15146-51.
Grallert, B; Nurse, P The ORC1 homolog orp1 in fission yeast plays a key role in regulating onset of S phase. Genes & development 1996;10(20):2644-54.
Yaffe, MP; Harata, D; Verde, F; Eddison, M; Toda, T; Nurse, P Microtubules mediate mitochondrial distribution in fission yeast. Proceedings of the National Academy of Sciences of the United States of America 1996;93(21):11664-8.
MacNeill, SA; Moreno, S; Reynolds, N; Nurse, P; Fantes, PA The fission yeast Cdc1 protein, a homologue of the small subunit of DNA polymerase delta, binds to Pol3 and Cdc27. The EMBO journal 1996;15(17):4613-28.
Woollard, A; Basi, G; Nurse, P A novel S phase inhibitor in fission yeast. The EMBO journal 1996;15(17):4603-12.
Stern, B; Nurse, P A quantitative model for the cdc2 control of S phase and mitosis in fission yeast. Trends in genetics : TIG 1996;12(9):345-50.
Wuarin, J; Nurse, P Regulating S phase: CDKs, licensing and proteolysis. Cell 1996;85(6):785-7.
Fisher, DL; Nurse, P A single fission yeast mitotic cyclin B p34cdc2 kinase promotes both S-phase and mitosis in the absence of G1 cyclins. The EMBO journal 1996;15(4):850-60.
Chang, F; Nurse, P How fission yeast fission in the middle. Cell 1996;84(2):191-4.
Chang, F; Woollard, A; Nurse, P Isolation and characterization of fission yeast mutants defective in the assembly and placement of the contractile actin ring. Journal of cell science 1996;109 ( Pt 1)():131-42.
Nurse, P The central role of a CDK in controlling the fission yeast cell cycle. Harvey lectures 1996;92():55-64.
Correa-Bordes, J; Nurse, P p25rum1 orders S phase and mitosis by acting as an inhibitor of the p34cdc2 mitotic kinase. Cell 1995;83(6):1001-9.
Verde, F; Mata, J; Nurse, P Fission yeast cell morphogenesis: identification of new genes and analysis of their role during the cell cycle. The Journal of cell biology 1995;131(6 Pt 1):1529-38.
Nishitani, H; Nurse, P p65cdc18 plays a major role controlling the initiation of DNA replication in fission yeast. Cell 1995;83(3):397-405.
Labib, K; Moreno, S; Nurse, P Interaction of cdc2 and rum1 regulates Start and S-phase in fission yeast. Journal of cell science 1995;108 ( Pt 10)():3285-94.
D’Urso, G; Grallert, B; Nurse, P DNA polymerase alpha, a component of the replication initiation complex, is essential for the checkpoint coupling S phase to mitosis in fission yeast. Journal of cell science 1995;108 ( Pt 9)():3109-18.
Hayles, J; Nurse, P A pre-start checkpoint preventing mitosis in fission yeast acts independently of p34cdc2 tyrosine phosphorylation. The EMBO journal 1995;14(12):2760-71.
Woollard, A; Nurse, P G1 regulation and checkpoints operating around START in fission yeast. BioEssays : news and reviews in molecular, cellular and developmental biology 1995;17(6):481-90.
Labib, K; Craven, RA; Crawford, K; Nurse, P Dominant mutants identify new roles for p34cdc2 in mitosis. The EMBO journal 1995;14(10):2155-65.
Endicott, JA; Nurse, P The cell cycle and suc1: from structure to function? Structure (London, England : 1993) 1995;3(4):321-5.
Fisher, D; Nurse, P Cyclins of the fission yeast Schizosaccharomyces pombe. Seminars in cell biology 1995;6(2):73-8.
Endicott, JA; Noble, ME; Garman, EF; Brown, N; Rasmussen, B; Nurse, P; Johnson, LN The crystal structure of p13suc1, a p34cdc2-interacting cell cycle control protein. The EMBO journal 1995;14(5):1004-14.
Kohli, J; Nurse, P Genetic nomenclature guide. Schizosaccharomyces pombe. Trends in genetics : TIG 1995;():9-10.
D’Urso, G; Nurse, P Checkpoints in the cell cycle of fission yeast. Current opinion in genetics & development 1995;5(1):12-6.
Wilkinson, CR; Bartlett, R; Nurse, P; Bird, AP The fission yeast gene pmt1+ encodes a DNA methyltransferase homologue. Nucleic acids research 1995;23(2):203-10.
O’Connell, MJ; Nurse, P How cells know they are in G1 or G2. Current opinion in cell biology 1994;6(6):867-71.
Carr, AM; Dorrington, SM; Hindley, J; Phear, GA; Aves, SJ; Nurse, P Analysis of a histone H2A variant from fission yeast: evidence for a role in chromosome stability. Molecular & general genetics : MGG 1994;245(5):628-35.
Nurse, P Ordering S phase and M phase in the cell cycle. Cell 1994;79(4):547-50.
O’Connell, MJ; Norbury, C; Nurse, P Premature chromatin condensation upon accumulation of NIMA. The EMBO journal 1994;13(20):4926-37.
Forsburg, SL; Nurse, P The fission yeast cdc19+ gene encodes a member of the MCM family of replication proteins. Journal of cell science 1994;107 ( Pt 10)():2779-88.
Hayles, J; Fisher, D; Woollard, A; Nurse, P Temporal order of S phase and mitosis in fission yeast is determined by the state of the p34cdc2-mitotic B cyclin complex. Cell 1994;78(5):813-22.
Nurse, P Fission yeast morphogenesis–posing the problems. Molecular biology of the cell 1994;5(6):613-6.
Snell, V; Nurse, P Genetic analysis of cell morphogenesis in fission yeast–a role for casein kinase II in the establishment of polarized growth. The EMBO journal 1994;13(9):2066-74.
Paris, J; Leplatois, P; Nurse, P Study of the higher eukaryotic gene function CDK2 using fission yeast. Journal of cell science 1994;107 ( Pt 3)():615-23.
Forsburg, SL; Nurse, P Analysis of the Schizosaccharomyces pombe cyclin puc1: evidence for a role in cell cycle exit. Journal of cell science 1994;107 ( Pt 3)():601-13.
Sazer, S; Nurse, P A fission yeast RCC1-related protein is required for the mitosis to interphase transition. The EMBO journal 1994;13(3):606-15.
Endicott, JA; Nurse, P; Johnson, LN Mutational analysis supports a structural model for the cell cycle protein kinase p34. Protein engineering 1994;7(2):243-53.
Kodaki, T; Woscholski, R; Emr, S; Waterfield, MD; Nurse, P; Parker, PJ Mammalian phosphatidylinositol 3’-kinase induces a lethal phenotype on expression in Schizosaccharomyces pombe; comparison with the VPS34 gene product. European journal of biochemistry / FEBS 1994;219(3):775-80.
Moreno, S; Nurse, P Regulation of progression through the G1 phase of the cell cycle by the rum1+ gene. Nature 1994;367(6460):236-42.
Moreno, S; Labib, K; Correa, J; Nurse, P Regulation of the cell cycle timing of Start in fission yeast by the rum1+ gene. Journal of cell science. Supplement 1994;18():63-8.
Chang, F; Nurse, P Finishing the cell cycle: control of mitosis and cytokinesis in fission yeast. Trends in genetics : TIG 1993;9(10):333-5.
Nurse, P The Wellcome Lecture, 1992. Cell cycle control. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1993;341(1298):449-54.
MacNeill, SA; Nurse, P Genetic analysis of human p34CDC2 function in fission yeast. Molecular & general genetics : MGG 1993;240(3):315-22.
Kelly, TJ; Martin, GS; Forsburg, SL; Stephen, RJ; Russo, A; Nurse, P The fission yeast cdc18+ gene product couples S phase to START and mitosis. Cell 1993;74(2):371-82.
Meddins, AK; Nurse, P; Gould, KL Analysis of 5’ flanking sequences from the Schizosaccharomyces pombe cdc2 gene. Gene 1993;127(1):145-8.
Wei, W; Nurse, P; Broek, D Yeast cells can enter a quiescent state through G1, S, G2, or M phase of the cell cycle. Cancer research 1993;53(8):1867-70.
Grallert, B; Nurse, P; Patterson, TE A study of integrative transformation in Schizosaccharomyces pombe. Molecular & general genetics : MGG 1993;238(1-2):26-32.
Labib, K; Nurse, P Cell cycle: bring on the phosphatases. Current biology : CB 1993;3(3):164-6.
Enoch, T; Carr, A; Nurse, P Checkpoint check. Nature 1993;361(6407):26.
MacNeill, SA; Nurse, P Mutational analysis of the fission yeast p34cdc2 protein kinase gene. Molecular & general genetics : MGG 1993;236(2-3):415-26.
Snell, V; Nurse, P Investigations into the control of cell form and polarity: the use of morphological mutants in fission yeast. Development (Cambridge, England). Supplement 1993;():289-99.
Kelly, TJ; Nurse, P; Forsburg, SL Coupling DNA replication to the cell cycle. Cold Spring Harbor symposia on quantitative biology 1993;58():637-44.
Waseem, NH; Labib, K; Nurse, P; Lane, DP Isolation and analysis of the fission yeast gene encoding polymerase delta accessory protein PCNA. The EMBO journal 1992;11(13):5111-20.
Enoch, T; Carr, AM; Nurse, P Fission yeast genes involved in coupling mitosis to completion of DNA replication. Genes & development 1992;6(11):2035-46.
Alphey, L; Jimenez, J; White-Cooper, H; Dawson, I; Nurse, P; Glover, DM twine, a cdc25 homolog that functions in the male and female germline of Drosophila. Cell 1992;69(6):977-88.
Fleig, UN; Gould, KL; Nurse, P A dominant negative allele of p34cdc2 shows altered phosphoamino acid content and sequesters p56cdc13 cyclin. Molecular and cellular biology 1992;12(5):2295-301.
Nurse, P Ciba Medal Lecture. Eukaryotic cell-cycle control. Biochemical Society transactions 1992;20(2):239-42.
Ayscough, K; Hayles, J; MacNeill, SA; Nurse, P Cold-sensitive mutants of p34cdc2 that suppress a mitotic catastrophe phenotype in fission yeast. Molecular & general genetics : MGG 1992;232(3):344-50.
Norbury, C; Nurse, P Animal cell cycles and their control. Annual review of biochemistry 1992;61():441-70.
Hayles, J; Nurse, P Genetics of the fission yeast Schizosaccharomyces pombe. Annual review of genetics 1992;26():373-402.
Nurse, P Cell cycle. Checkpoints and spindles. Nature 1991;354(6352):356-8.
Norbury, C; Blow, J; Nurse, P Regulatory phosphorylation of the p34cdc2 protein kinase in vertebrates. The EMBO journal 1991;10(11):3321-9.
Gould, KL; Moreno, S; Owen, DJ; Sazer, S; Nurse, P Phosphorylation at Thr167 is required for Schizosaccharomyces pombe p34cdc2 function. The EMBO journal 1991;10(11):3297-309.
MacNeill, SA; Creanor, J; Nurse, P Isolation, characterisation and molecular cloning of new mutant alleles of the fission yeast p34cdc2+ protein kinase gene: identification of temperature-sensitive G2-arresting alleles. Molecular & general genetics : MGG 1991;229(1):109-18.
Nurse, P The Florey Lecture, 1990. How is the cell division cycle regulated? Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1991;332(1264):271-6.
Enoch, T; Nurse, P Coupling M phase and S phase: controls maintaining the dependence of mitosis on chromosome replication. Cell 1991;65(6):921-3.
Forsburg, SL; Nurse, P Identification of a G1-type cyclin puc1+ in the fission yeast Schizosaccharomyces pombe. Nature 1991;351(6323):245-8.
Moreno, S; Nurse, P Clues to action of cdc25 protein. Nature 1991;351(6323):194.
Fleig, UN; Nurse, P Expression of a dominant negative allele of cdc2 prevents activation of the endogenous p34cdc2 kinase. Molecular & general genetics : MGG 1991;226(3):432-40.
Enoch, T; Peter, M; Nurse, P; Nigg, EA p34cdc2 acts as a lamin kinase in fission yeast. The Journal of cell biology 1991;112(5):797-807.
Norbury, C; Nurse, P Cyclins and cell cycle control. Current biology : CB 1991;1(1):23-4.
Feilotter, H; Nurse, P; Young, PG Genetic and molecular analysis of cdr1/nim1 in Schizosaccharomyces pombe. Genetics 1991;127(2):309-18.
Broek, D; Bartlett, R; Crawford, K; Nurse, P Involvement of p34cdc2 in establishing the dependency of S phase on mitosis. Nature 1991;349(6308):388-93.
Moreno, S; Klar, A; Nurse, P Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. Methods in enzymology 1991;194():795-823.
Enoch, T; Gould, KL; Nurse, P Mitotic checkpoint control in fission yeast. Cold Spring Harbor symposia on quantitative biology 1991;56():409-16.
Forsburg, SL; Nurse, P Cell cycle regulation in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe. Annual review of cell biology 1991;7():227-56.
Gould, KL; Moreno, S; Tonks, NK; Nurse, P Complementation of the mitotic activator, p80cdc25, by a human protein-tyrosine phosphatase. Science (New York, N.Y.) 1990;250(4987):1573-6.
Jimenez, J; Alphey, L; Nurse, P; Glover, DM Complementation of fission yeast cdc2ts and cdc25ts mutants identifies two cell cycle genes from Drosophila: a cdc2 homologue and string. The EMBO journal 1990;9(11):3565-71.
Th’ng, JP; Wright, PS; Hamaguchi, J; Lee, MG; Norbury, CJ; Nurse, P; Bradbury, EM The FT210 cell line is a mouse G2 phase mutant with a temperature-sensitive CDC2 gene product. Cell 1990;63(2):313-24.
Bartlett, R; Nurse, P Yeast as a model system for understanding the control of DNA replication in Eukaryotes. BioEssays : news and reviews in molecular, cellular and developmental biology 1990;12(10):457-63.
Blow, JJ; Nurse, P A cdc2-like protein is involved in the initiation of DNA replication in Xenopus egg extracts. Cell 1990;62(5):855-62.
Moreno, S; Nurse, P Substrates for p34cdc2: in vivo veritas? Cell 1990;61(4):549-51.
Moreno, S; Nurse, P; Russell, P Regulation of mitosis by cyclic accumulation of p80cdc25 mitotic inducer in fission yeast. Nature 1990;344(6266):549-52.
Nurse, P Universal control mechanism regulating onset of M-phase. Nature 1990;344(6266):503-8.
Enoch, T; Nurse, P Mutation of fission yeast cell cycle control genes abolishes dependence of mitosis on DNA replication. Cell 1990;60(4):665-73.
Norbury, C; Nurse, P Controls of cell proliferation in yeast and animals. Ciba Foundation symposium 1990;150():168-77; discussion 177-83.
Bailly, E; Dorée, M; Nurse, P; Bornens, M p34cdc2 is located in both nucleus and cytoplasm; part is centrosomally associated at G2/M and enters vesicles at anaphase. The EMBO journal 1989;8(13):3985-95.
Gould, KL; Nurse, P Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis. Nature 1989;342(6245):39-45.
Hayles, J; Nurse, P A review of mitosis in the fission yeast Schizosaccharomyces pombe. Experimental cell research 1989;184(2):273-86.
Langan, TA; Gautier, J; Lohka, M; Hollingsworth, R; Moreno, S; Nurse, P; Maller, J; Sclafani, RA Mammalian growth-associated H1 histone kinase: a homolog of cdc2+/CDC28 protein kinases controlling mitotic entry in yeast and frog cells. Molecular and cellular biology 1989;9(9):3860-8.
Moreno, S; Hayles, J; Nurse, P Regulation of p34cdc2 protein kinase during mitosis. Cell 1989;58(2):361-72.
Norbury, CJ; Nurse, P Control of the higher eukaryote cell cycle by p34cdc2 homologues. Biochimica et biophysica acta 1989;989(1):85-95.
Carr, AM; MacNeill, SA; Hayles, J; Nurse, P Molecular cloning and sequence analysis of mutant alleles of the fission yeast cdc2 protein kinase gene: implications for cdc2+ protein structure and function. Molecular & general genetics : MGG 1989;218(1):41-9.
MacNeill, SA; Nurse, P Genetic interactions in the control of mitosis in fission yeast. Current genetics 1989;16(1):1-6.
Gautier, J; Matsukawa, T; Nurse, P; Maller, J Dephosphorylation and activation of Xenopus p34cdc2 protein kinase during the cell cycle. Nature 1989;339(6226):626-9.
Labbe, JC; Picard, A; Peaucellier, G; Cavadore, JC; Nurse, P; Doree, M Purification of MPF from starfish: identification as the H1 histone kinase p34cdc2 and a possible mechanism for its periodic activation. Cell 1989;57(2):253-63.
Simanis, V; Nurse, P Characterization of the fission yeast cdc10+ protein that is required for commitment to the cell cycle. Journal of cell science 1989;92 ( Pt 1)():51-6.
Maller, J; Gautier, J; Langan, TA; Lohka, MJ; Shenoy, S; Shalloway, D; Nurse, P Maturation-promoting factor and the regulation of the cell cycle. Journal of cell science. Supplement 1989;12():53-63.
Moreno, S; Hayles, J; Nurse, P Regulation of the cell cycle timing of mitosis. Journal of cell science. Supplement 1989;12():1-8.
Hagan, I; Hayles, J; Nurse, P Cloning and sequencing of the cyclin-related cdc13+ gene and a cytological study of its role in fission yeast mitosis. Journal of cell science 1988;91 ( Pt 4)():587-95.
Lee, M; Nurse, P Cell cycle control genes in fission yeast and mammalian cells. Trends in genetics : TIG 1988;4(10):287-90.
Labbe, JC; Lee, MG; Nurse, P; Picard, A; Doree, M Activation at M-phase of a protein kinase encoded by a starfish homologue of the cell cycle control gene cdc2+. Nature 1988;335(6187):251-4.
Gautier, J; Norbury, C; Lohka, M; Nurse, P; Maller, J Purified maturation-promoting factor contains the product of a Xenopus homolog of the fission yeast cell cycle control gene cdc2+. Cell 1988;54(3):433-9.
Lee, MG; Norbury, CJ; Spurr, NK; Nurse, P Regulated expression and phosphorylation of a possible mammalian cell-cycle control protein. Nature 1988;333(6174):676-9.
Jones, RH; Moreno, S; Nurse, P; Jones, NC Expression of the SV40 promoter in fission yeast: identification and characterization of an AP-1-like factor. Cell 1988;53(4):659-67.
Spurr, NK; Gough, A; Goodfellow, PJ; Goodfellow, PN; Lee, MG; Nurse, P Evolutionary conservation of the human homologue of the yeast cell cycle control gene cdc2 and assignment of Cd2 to chromosome 10. Human genetics 1988;78(4):333-7.
Simanis, V; Hayles, J; Nurse, P Control over the onset of DNA synthesis in fission yeast. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1987;317(1187):507-16.
Nurse, P Cell reproduction. British medical journal (Clinical research ed.) 1987;295(6605):1037-8.
Russell, P; Nurse, P The mitotic inducer nim1+ functions in a regulatory network of protein kinase homologs controlling the initiation of mitosis. Cell 1987;49(4):569-76.
Russell, P; Nurse, P Negative regulation of mitosis by wee1+, a gene encoding a protein kinase homolog. Cell 1987;49(4):559-67.
Lee, MG; Nurse, P Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2. Nature 1987;327(6117):31-5.
Lee, MG; Nurse, P Cell cycle genes of the fission yeast. Science progress 1987;71(281 Pt 1):1-14.
Simanis, V; Carr, AM; Goss, M; Lee, MG; MacNeill, SA; Nurse, P Cell cycle regulation in yeasts and man: towards a unifying mechanism. Antonie van Leeuwenhoek 1987;53(5):319-23.
Hayles, J; Aves, S; Nurse, P suc1 is an essential gene involved in both the cell cycle and growth in fission yeast. The EMBO journal 1986;5(12):3373-9.
White, JH; Barker, DG; Nurse, P; Johnston, LH Periodic transcription as a means of regulating gene expression during the cell cycle: contrasting modes of expression of DNA ligase genes in budding and fission yeast. The EMBO journal 1986;5(7):1705-9.
Russell, P; Nurse, P Schizosaccharomyces pombe and Saccharomyces cerevisiae: a look at yeasts divided. Cell 1986;45(6):781-2.
Simanis, V; Nurse, P The cell cycle control gene cdc2+ of fission yeast encodes a protein kinase potentially regulated by phosphorylation. Cell 1986;45(2):261-8.
Russell, P; Nurse, P cdc25+ functions as an inducer in the mitotic control of fission yeast. Cell 1986;45(1):145-53.
Wright, A; Maundrell, K; Heyer, WD; Beach, D; Nurse, P Vectors for the construction of gene banks and the integration of cloned genes in Schizosaccharomyces pombe and Saccharomyces cerevisiae. Plasmid 1986;15(2):156-8.
Durkacz, B; Carr, A; Nurse, P Transcription of the cdc2 cell cycle control gene of the fission yeast Schizosaccharomyces pombe. The EMBO journal 1986;5(2):369-73.
Hayles, J; Beach, D; Durkacz, B; Nurse, P The fission yeast cell cycle control gene cdc2: isolation of a sequence suc1 that suppresses cdc2 mutant function. Molecular & general genetics : MGG 1986;202(2):291-3.
Hayles, J; Nurse, P Cell cycle regulation in yeast. Journal of cell science. Supplement 1986;4():155-70.
Johnston, LH; Barker, DG; Nurse, P Cloning and characterization of the Schizosaccharomyces pombe DNA ligase gene CDC17. Gene 1986;41(2-3):321-5.
Käufer, NF; Simanis, V; Nurse, P Fission yeast Schizosaccharomyces pombe correctly excises a mammalian RNA transcript intervening sequence. Nature 1985;318(6041):78-80.
Mitchison, JM; Nurse, P Growth in cell length in the fission yeast Schizosaccharomyces pombe. Journal of cell science 1985;75():357-76.
Nurse, P Yeast aids cancer research. Nature 1985;313(6004):631-2.
Aves, SJ; Durkacz, BW; Carr, A; Nurse, P Cloning, sequencing and transcriptional control of the Schizosaccharomyces pombe cdc10 ’start’ gene. The EMBO journal 1985;4(2):457-63.
Maundrell, K; Nurse, P; Schönholzer, F; Schweingruber, ME Cloning and characterization of two genes restoring acid phosphatase activity in pho1- mutants of Schizosaccharomyces pombe. Gene 1985;39(2-3):223-30.
Nurse, P Coordinating histone transcription and DNA replication. Nature 1983;302(5907):378.
Beach, D; Durkacz, B; Nurse, P Functionally homologous cell cycle control genes in budding and fission yeast. Nature 1982;300(5894):706-9.
Beach, D; Nurse, P; Egel, R Molecular rearrangement of mating-type genes in fission yeast. Nature 1982;296(5858):682-3.
Beach, D; Piper, M; Nurse, P Construction of a Schizosaccharomyces pombe gene bank in a yeast bacterial shuttle vector and its use to isolate genes by complementation. Molecular & general genetics : MGG 1982;187(2):326-9.
Nurse, P; Bissett, Y Gene required in G1 for commitment to cell cycle and in G2 for control of mitosis in fission yeast. Nature 1981;292(5823):558-60.
Nasmyth, K; Nurse, P Cell division cycle mutants altered in DNA replication and mitosis in the fission yeast Schizosaccharomyces pombe. Molecular & general genetics : MGG 1981;182(1):119-24.
Benitez, T; Nurse, P; Mitchison, JM Arginase and sucrase potential in the fission yeast Schizosaccharomyces pombe. Journal of cell science 1980;46():399-431.
Nurse, P; Thuriaux, P Regulatory genes controlling mitosis in the fission yeast Schizosaccharomyces pombe. Genetics 1980;96(3):627-37.
Nurse, P Cell cycle control–both deterministic and probabilistic? Nature 1980;286(5768):9-10.
Nasmyth, K; Nurse, P; Fraser, RS The effect of cell mass on the cell cycle timing and duration of S-phase in fission yeast. Journal of cell science 1979;39():215-33.
Barnes, A; Nurse, P; Fraser, RS Analysis of the significance of a periodic, cell size-controlled doubling in rates of macromolecular synthesis for the control of balanced exponential growth of fission yeast cells. Journal of cell science 1979;35():41-51.
Fraser, RS; Nurse, P Altered patterns of ribonucleic acid synthesis during the cell cycle: a mechanism compensating for variation in gene concentration. Journal of cell science 1979;35():25-40.
Minet, M; Nurse, P; Thuriaux, P; Mitchison, JM Uncontrolled septation in a cell division cycle mutant of the fission yeast Schizosaccharomyces pombe. Journal of bacteriology 1979;137(1):440-6.
Fantes, PA; Nurse, P Control of the timing of cell division in fission yeast. Cell size mutants reveal a second control pathway. Experimental cell research 1978;115(2):317-29.
Thuriaux, P; Nurse, P; Carter, B Mutants altered in the control co-ordinating cell division with cell growth in the fission yeast Schizosaccharomyces pombe. Molecular & general genetics : MGG 1978;161(2):215-20.
Fraser, RS; Nurse, P Novel cell cycle control of RNA synthesis in yeast. Nature 1978;271(5647):726-30.
Fantes, P; Nurse, P Control of cell size at division in fission yeast by a growth-modulated size control over nuclear division. Experimental cell research 1977;107(2):377-86.
Nurse, P; Thuriaux, P Controls over the timing of DNA replication during the cell cycle of fission yeast. Experimental cell research 1977;107(2):365-75.
Nurse, P Cell-cycle control in yeasts [proceedings]. Biochemical Society transactions 1977;5(4):1191-3.
Nurse, P; Thuriaux, P; Nasmyth, K Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombe. Molecular & general genetics : MGG 1976;146(2):167-78.
Nurse, P Genetic control of cell size at cell division in yeast. Nature 1975;256(5518):547-51.
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