Christiane Nüsslein-Volhard

Christiane Nüsslein-Volhard is a German biologist and the Nobel Laureate in Physiology or Medicine 1995. She shared the honor with Eric Wieschaus and Edward B. Lewis. Nüsslein-Volhard and Eric Wieschaus worked on identifying genes involved in the development of embryosof Drosophila melanogaster (fruit fly).  Their research on the genetic control of embryogenesis led to the identification of steps and mechanisms involved in the formation of body segments.

Christiane Nüsslein-Volhard received the Albert Lasker Award for Basic Medical Research in 1991. She is also the author of different books, namely “Of Fish, Fly, Worm, and Man: Lessons from Developmental Biology for Human Gene Function and Disease(2000)”, Zebrafish: A Practical Approach (2002, with Ralf Dahm) and Coming to Life: How Genes Drive Development (2006).

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1986 Leibniz Prize of the German Research Foundation

1986 Franz Vogt Prize of the University of Gießen

1988 Brooks Lecturer, Harvard Medical School

1989 Carus Medal of the German Academy of Sciences Leopoldina, Halle

1989 Carus Prize of the City of Schweinfurt

1989 Honorary Professor, University of Tübingen

1989 Silliman Lecturer, Yale University

1990 Rosenstiel Medal, Brandeis University

1990 Sc. D., Yale University

1990 Mattia Award, Roche Institute, New Jersey

1991 Dr. h.c., Utrecht University

1991 Dr. h.c., Princeton University

1991 Dunham Lecturer, Harvard Medical School

1991 Harvey Lecturer, Rockefeller University

1991 Albert Lasker Medical Research Award, New York

1992 Prix Louis Jeantet de Médecine, Geneva

1992 Alfred P. Sloan Jr. Prize, General Motors Cancer Research Foundation

1992 Dr. Otto Bayer Prize, Leverkusen

1992 Otto Warburg Medal of the Foundation of Biological Chemistry, Rostock

1992 Louisa Gross Horwitz Prize, Columbia University

1992 Gregor Mendel Medal of the Genetical Society, England

1993 Dr. h.c., University of Freiburg

1993 Ernst Schering Prize, Ernst Schering Research Foundation, Germany

1993 Dr. h.c., Harvard University

1993 Sir Hans Krebs Medal of the FEBS

1993 Theodor Boveri Prize of the Physico-Medica-Foundation of the University of Würzburg

1993 Bertner Award, Anderson Cancer Research Center, Houston

1994 Distinguished Service Medal (1st class) of the Order of Merit of the Federal Republic of Germany

1995 Nobel Prize for Medicine and Physiology together with Edward B. Lewis (California Institute of Technology) and Eric Wischaus (Princeton University)

1995 Goethe Medal of the City of Frankfurt/Main

1996 Great Distinguished Service Cross of the Order of Merit of the Federal Republic of Germany

1997 Pour le Mérite

1997 Dr. h.c., University of Munich (LMU)

Kenji Saito; Kellee R Siegfried; Christiane Nüsslein-Volhard; Noriyoshi Sakai Isolation and cytogenetic characterization of zebrafish meiotic prophase I mutants. Developmental dynamics : an official publication of the American Association of Anatomists 2011;240(7):1779-92.

Hélène Doerflinger; Nina Vogt; Isabel L Torres; Vincent Mirouse; Iris Koch; Christiane Nüsslein-Volhard; Daniel St Johnston Bazooka is required for polarisation of the Drosophila anterior-posterior axis. Development (Cambridge, England) 2010;137(10):1765-73.

Sven Reischauer; Mitchell P Levesque; Christiane Nüsslein-Volhard; Mahendra Sonawane Lgl2 executes its function as a tumor suppressor by regulating ErbB signaling in the zebrafish epidermis. PLoS genetics 2009;5(11):e1000720.

Nicolas Rohner; Miklós Bercsényi; László Orbán; Maria E Kolanczyk; Dirk Linke; Michael Brand; Christiane Nüsslein-Volhard; Matthew P Harris Duplication of fgfr1 permits Fgf signaling to serve as a target for selection during domestication. Current biology : CB 2009;19(19):1642-7.

Jana Krauss; Sonia López de Quinto; Christiane Nüsslein-Volhard; Anne Ephrussi Myosin-V regulates oskar mRNA localization in the Drosophila oocyte. Current biology : CB 2009;19(12):1058-63.

Mahendra Sonawane; Hans Martin-Maischein; Heinz Schwarz; Christiane Nüsslein-Volhard Lgl2 and E-cadherin act antagonistically to regulate hemidesmosome formation during epidermal development in zebrafish. Development (Cambridge, England) 2009;136(8):1231-40.

Agustin Rojas-Muñoz; Shibani Rajadhyksha; Darren Gilmour; Frauke van Bebber; Christopher Antos; Concepción Rodríguez Esteban; Christiane Nüsslein-Volhard; Juan Carlos Izpisúa Belmonte ErbB2 and ErbB3 regulate amputation-induced proliferation and migration during vertebrate regeneration. Developmental biology 2009;327(1):177-90.

Caghan Kizil; Georg W Otto; Robert Geisler; Christiane Nüsslein-Volhard; Christopher L Antos Simplet controls cell proliferation and gene transcription during zebrafish caudal fin regeneration. Developmental biology 2009;325(2):329-40.

Kellee R Siegfried; Christiane Nüsslein-Volhard Germ line control of female sex determination in zebrafish. Developmental biology 2008;324(2):277-87.

Francesca Peri; Christiane Nüsslein-Volhard Live imaging of neuronal degradation by microglia reveals a role for v0-ATPase a1 in phagosomal fusion in vivo. Cell 2008;133(5):916-27.

Christiane Nüsslein-Volhard Women in science–passion and prejudice. Current biology : CB 2008;18(5):R185-7.

Matthew P Harris; Nicolas Rohner; Heinz Schwarz; Simon Perathoner; Peter Konstantinidis; Christiane Nüsslein-Volhard Zebrafish eda and edar mutants reveal conserved and ancestral roles of ectodysplasin signaling in vertebrates. PLoS genetics 2008;4(10):e1000206.

Nina Vogt; Iris Koch; Heinz Schwarz; Frank Schnorrer; Christiane Nüsslein-Volhard The gammaTuRC components Grip75 and Grip128 have an essential microtubule-anchoring function in the Drosophila germline. Development (Cambridge, England) 2006;133(20):3963-72.

Bernard Moussian; Erika Tång; Anna Tonning; Sigrun Helms; Heinz Schwarz; Christiane Nüsslein-Volhard; Anne E Uv Drosophila Knickkopf and Retroactive are needed for epithelial tube growth and cuticle differentiation through their specific requirement for chitin filament organization. Development (Cambridge, England) 2006;133(1):163-71.

Agustin Rojas-Muñoz; Ralf Dahm; Christiane Nüsslein-Volhard chokh/rx3 specifies the retinal pigment epithelium fate independently of eye morphogenesis. Developmental biology 2005;288(2):348-62.

Bernard Moussian; Johannes Söding; Heinz Schwarz; Christiane Nüsslein-Volhard Retroactive, a membrane-anchored extracellular protein related to vertebrate snake neurotoxin-like proteins, is required for cuticle organization in the larva of Drosophila melanogaster. Developmental dynamics : an official publication of the American Association of Anatomists 2005;233(3):1056-63.

Bernard Moussian; Heinz Schwarz; Slawomir Bartoszewski; Christiane Nüsslein-Volhard Involvement of chitin in exoskeleton morphogenesis in Drosophila melanogaster. Journal of morphology 2005;264(1):117-30.

Jeong-Soo Lee; Sophia von der Hardt; Melissa A Rusch; Sally E Stringer; Heather L Stickney; William S Talbot; Robert Geisler; Christiane Nüsslein-Volhard; Scott B Selleck; Chi-Bin Chien; et al. Axon sorting in the optic tract requires HSPG synthesis by ext2 (dackel) and extl3 (boxer). Neuron 2004;44(6):947-60.

Francisco Pelegri; Marcus P S Dekens; Stefan Schulte-Merker; Hans-Martin Maischein; Catrin Weiler; Christiane Nüsslein-Volhard Identification of recessive maternal-effect mutations in the zebrafish using a gynogenesis-based method. Developmental dynamics : an official publication of the American Association of Anatomists 2004;231(2):324-35.

Slawomir Bartoszewski; Stefan Luschnig; Isabelle Desjeux; Jörg Grosshans; Christiane Nüsslein-Volhard Drosophila p24 homologues eclair and baiser are necessary for the activity of the maternally expressed Tkv receptor during early embryogenesis. Mechanisms of development 2004;121(10):1259-73.

Stefan Luschnig; Bernard Moussian; Jana Krauss; Isabelle Desjeux; Josip Perkovic; Christiane Nüsslein-Volhard An F1 genetic screen for maternal-effect mutations affecting embryonic pattern formation in Drosophila melanogaster. Genetics 2004;167(1):325-42.

Darren Gilmour; Holger Knaut; Hans-Martin Maischein; Christiane Nüsslein-Volhard Towing of sensory axons by their migrating target cells in vivo. Nature neuroscience 2004;7(5):491-2.

Marcus P S Dekens; Francisco J Pelegri; Hans-Martin Maischein; Christiane Nüsslein-Volhard The maternal-effect gene futile cycle is essential for pronuclear congression and mitotic spindle assembly in the zebrafish zygote. Development (Cambridge, England) 2003;130(17):3907-16.

Florian Maderspacher; Christiane Nüsslein-Volhard Formation of the adult pigment pattern in zebrafish requires leopard and obelix dependent cell interactions. Development (Cambridge, England) 2003;130(15):3447-57.

Iphigenie Charatsi; Stefan Luschnig; Slawomir Bartoszewski; Christiane Nüsslein-Volhard; Bernard Moussian Krapfen/dMyd88 is required for the establishment of dorsoventral pattern in the Drosophila embryo. Mechanisms of development 2003;120(2):219-26.

Holger Knaut; Christian Werz; Robert Geisler; Christiane Nüsslein-Volhard A zebrafish homologue of the chemokine receptor Cxcr4 is a germ-cell guidance receptor. Nature 2003;421(6920):279-82.

Frank Schnorrer; Stefan Luschnig; Iris Koch; Christiane Nüsslein-Volhard Gamma-tubulin37C and gamma-tubulin ring complex protein 75 are essential for bicoid RNA localization during drosophila oogenesis. Developmental cell 2002;3(5):685-96.

Darren T Gilmour; Hans-Martin Maischein; Christiane Nüsslein-Volhard Migration and function of a glial subtype in the vertebrate peripheral nervous system. Neuron 2002;34(4):577-88.

Holger Knaut; Herbert Steinbeisser; Heinz Schwarz; Christiane Nüsslein-Volhard An evolutionary conserved region in the vasa 3’UTR targets RNA translation to the germ cells in the zebrafish. Current biology : CB 2002;12(6):454-66.

Scott A Holley; Dörthe Jülich; Gerd-Jörg Rauch; Robert Geisler; Christiane Nüsslein-Volhard her1 and the notch pathway function within the oscillator mechanism that regulates zebrafish somitogenesis. Development (Cambridge, England) 2002;129(5):1175-83.

H Roehl; C Nüsslein-Volhard Zebrafish pea3 and erm are general targets of FGF8 signaling. Current biology : CB 2001;11(7):503-7.

T Piotrowski; C Nüsslein-Volhard The endoderm plays an important role in patterning the segmented pharyngeal region in zebrafish (Danio rerio). Developmental biology 2000;225(2):339-56.

S A Holley; R Geisler; C Nüsslein-Volhard Control of her1 expression during zebrafish somitogenesis by a delta-dependent oscillator and an independent wave-front activity. Genes & development 2000;14(13):1678-90.

H Knaut; F Pelegri; K Bohmann; H Schwarz; C Nüsslein-Volhard Zebrafish vasa RNA but not its protein is a component of the germ plasm and segregates asymmetrically before germline specification. The Journal of cell biology 2000;149(4):875-88.

F Schnorrer; K Bohmann; C Nüsslein-Volhard The molecular motor dynein is involved in targeting swallow and bicoid RNA to the anterior pole of Drosophila oocytes. Nature cell biology 2000;2(4):185-90.

J Odenthal; F J van Eeden; P Haffter; P W Ingham; C Nüsslein-Volhard Two distinct cell populations in the floor plate of the zebrafish are induced by different pathways. Developmental biology 2000;219(2):350-63.

S Luschnig; J Krauss; K Bohmann; I Desjeux; C Nüsslein-Volhard The Drosophila SHC adaptor protein is required for signaling by a subset of receptor tyrosine kinases. Molecular cell 2000;5(2):231-41.

S A Holley; C Nüsslein-Volhard Somitogenesis in zebrafish. Current topics in developmental biology 2000;47():247-77.

F Pelegri; H Knaut; H M Maischein; S Schulte-Merker; C Nüsslein-Volhard A mutation in the zebrafish maternal-effect gene nebel affects furrow formation and vasa RNA localization. Current biology : CB 1999;9(24):1431-40.

C J Neumann; H Grandel; W Gaffield; S Schulte-Merker; C Nüsslein-Volhard Transient establishment of anteroposterior polarity in the zebrafish pectoral fin bud in the absence of sonic hedgehog activity. Development (Cambridge, England) 1999;126(21):4817-26.

J Grosshans; F Schnorrer; C Nüsslein-Volhard Oligomerisation of Tube and Pelle leads to nuclear localisation of dorsal. Mechanisms of development 1999;81(1-2):127-38.

R M Warga; C Nüsslein-Volhard Origin and development of the zebrafish endoderm. Development (Cambridge, England) 1999;126(4):827-38.

R M Warga; C Nüsslein-volhard spadetail-dependent cell compaction of the dorsal zebrafish blastula. Developmental biology 1998;203(1):116-21.

J Odenthal; C Nüsslein-Volhard fork head domain genes in zebrafish. Development genes and evolution 1998;208(5):245-58.

T Nicolson; A Rüsch; R W Friedrich; M Granato; J P Ruppersberg; C Nüsslein-Volhard Genetic analysis of vertebrate sensory hair cell mechanosensation: the zebrafish circler mutants. Neuron 1998;20(2):271-83.

F J van Eeden; S A Holley; P Haffter; C Nüsslein-Volhard Zebrafish segmentation and pair-rule patterning. Developmental genetics 1998;23(1):65-76.

M Wilsch-Bräuninger; H Schwarz; C Nüsslein-Volhard A sponge-like structure involved in the association and transport of maternal products during Drosophila oogenesis. The Journal of cell biology 1997;139(3):817-29.

J N Chen; F J van Eeden; K S Warren; A Chin; C Nüsslein-Volhard; P Haffter; M C Fishman Left-right pattern of cardiac BMP4 may drive asymmetry of the heart in zebrafish. Development (Cambridge, England) 1997;124(21):4373-82.

C P Heisenberg; C Nüsslein-Volhard The function of silberblick in the positioning of the eye anlage in the zebrafish embryo. Developmental biology 1997;184(1):85-94.

D Ferrandon; I Koch; E Westhof; C Nüsslein-Volhard RNA-RNA interaction is required for the formation of specific bicoid mRNA 3’ UTR-STAUFEN ribonucleoprotein particles. The EMBO journal 1997;16(7):1751-8.

T Trowe; S Klostermann; H Baier; M Granato; A D Crawford; B Grunewald; H Hoffmann; R O Karlstrom; S U Meyer; B Müller; et al. Mutations disrupting the ordering and topographic mapping of axons in the retinotectal projection of the zebrafish, Danio rerio. Development (Cambridge, England) 1996;123():439-50.

R O Karlstrom; T Trowe; S Klostermann; H Baier; M Brand; A D Crawford; B Grunewald; P Haffter; H Hoffmann; S U Meyer; et al. Zebrafish mutations affecting retinotectal axon pathfinding. Development (Cambridge, England) 1996;123():427-38.

H Baier; S Klostermann; T Trowe; R O Karlstrom; C Nüsslein-Volhard; F Bonhoeffer Genetic dissection of the retinotectal projection. Development (Cambridge, England) 1996;123():415-25.

M Granato; F J van Eeden; U Schach; T Trowe; M Brand; M Furutani-Seiki; P Haffter; M Hammerschmidt; C P Heisenberg; Y J Jiang; et al. Genes controlling and mediating locomotion behavior of the zebrafish embryo and larva. Development (Cambridge, England) 1996;123():399-413.

J Odenthal; K Rossnagel; P Haffter; R N Kelsh; E Vogelsang; M Brand; F J van Eeden; M Furutani-Seiki; M Granato; M Hammerschmidt; et al. Mutations affecting xanthophore pigmentation in the zebrafish, Danio rerio. Development (Cambridge, England) 1996;123():391-8.

R N Kelsh; M Brand; Y J Jiang; C P Heisenberg; S Lin; P Haffter; J Odenthal; M C Mullins; F J van Eeden; M Furutani-Seiki; et al. Zebrafish pigmentation mutations and the processes of neural crest development. Development (Cambridge, England) 1996;123():369-89.

T Piotrowski; T F Schilling; M Brand; Y J Jiang; C P Heisenberg; D Beuchle; H Grandel; F J van Eeden; M Furutani-Seiki; M Granato; et al. Jaw and branchial arch mutants in zebrafish II: anterior arches and cartilage differentiation. Development (Cambridge, England) 1996;123():345-56.

T F Schilling; T Piotrowski; H Grandel; M Brand; C P Heisenberg; Y J Jiang; D Beuchle; M Hammerschmidt; D A Kane; M C Mullins; et al. Jaw and branchial arch mutants in zebrafish I: branchial arches. Development (Cambridge, England) 1996;123():329-44.

D G Ransom; P Haffter; J Odenthal; A Brownlie; E Vogelsang; R N Kelsh; M Brand; F J van Eeden; M Furutani-Seiki; M Granato; et al. Characterization of zebrafish mutants with defects in embryonic hematopoiesis. Development (Cambridge, England) 1996;123():311-9.

J N Chen; P Haffter; J Odenthal; E Vogelsang; M Brand; F J van Eeden; M Furutani-Seiki; M Granato; M Hammerschmidt; C P Heisenberg; et al. Mutations affecting the cardiovascular system and other internal organs in zebrafish. Development (Cambridge, England) 1996;123():293-302.

F J van Eeden; M Granato; U Schach; M Brand; M Furutani-Seiki; P Haffter; M Hammerschmidt; C P Heisenberg; Y J Jiang; D A Kane; et al. Genetic analysis of fin formation in the zebrafish, Danio rerio. Development (Cambridge, England) 1996;123():255-62.

T T Whitfield; M Granato; F J van Eeden; U Schach; M Brand; M Furutani-Seiki; P Haffter; M Hammerschmidt; C P Heisenberg; Y J Jiang; et al. Mutations affecting development of the zebrafish inner ear and lateral line. Development (Cambridge, England) 1996;123():241-54.

M Furutani-Seiki; Y J Jiang; M Brand; C P Heisenberg; C Houart; D Beuchle; F J van Eeden; M Granato; P Haffter; M Hammerschmidt; et al. Neural degeneration mutants in the zebrafish, Danio rerio. Development (Cambridge, England) 1996;123():229-39.

Y J Jiang; M Brand; C P Heisenberg; D Beuchle; M Furutani-Seiki; R N Kelsh; R M Warga; M Granato; P Haffter; M Hammerschmidt; et al. Mutations affecting neurogenesis and brain morphology in the zebrafish, Danio rerio. Development (Cambridge, England) 1996;123():205-16.

M Brand; C P Heisenberg; Y J Jiang; D Beuchle; K Lun; M Furutani-Seiki; M Granato; P Haffter; M Hammerschmidt; D A Kane; et al. Mutations in zebrafish genes affecting the formation of the boundary between midbrain and hindbrain. Development (Cambridge, England) 1996;123():179-90.

F J van Eeden; M Granato; U Schach; M Brand; M Furutani-Seiki; P Haffter; M Hammerschmidt; C P Heisenberg; Y J Jiang; D A Kane; et al. Mutations affecting somite formation and patterning in the zebrafish, Danio rerio. Development (Cambridge, England) 1996;123():153-64.

M Hammerschmidt; F Pelegri; M C Mullins; D A Kane; M Brand; F J van Eeden; M Furutani-Seiki; M Granato; P Haffter; C P Heisenberg; et al. Mutations affecting morphogenesis during gastrulation and tail formation in the zebrafish, Danio rerio. Development (Cambridge, England) 1996;123():143-51.

M Brand; C P Heisenberg; R M Warga; F Pelegri; R O Karlstrom; D Beuchle; A Picker; Y J Jiang; M Furutani-Seiki; F J van Eeden; et al. Mutations affecting development of the midline and general body shape during zebrafish embryogenesis. Development (Cambridge, England) 1996;123():129-42.

J Odenthal; P Haffter; E Vogelsang; M Brand; F J van Eeden; M Furutani-Seiki; M Granato; M Hammerschmidt; C P Heisenberg; Y J Jiang; et al. Mutations affecting the formation of the notochord in the zebrafish, Danio rerio. Development (Cambridge, England) 1996;123():103-15.

M Hammerschmidt; F Pelegri; M C Mullins; D A Kane; F J van Eeden; M Granato; M Brand; M Furutani-Seiki; P Haffter; C P Heisenberg; et al. dino and mercedes, two genes regulating dorsal development in the zebrafish embryo. Development (Cambridge, England) 1996;123():95-102.

M C Mullins; M Hammerschmidt; D A Kane; J Odenthal; M Brand; F J van Eeden; M Furutani-Seiki; M Granato; P Haffter; C P Heisenberg; et al. Genes establishing dorsoventral pattern formation in the zebrafish embryo: the ventral specifying genes. Development (Cambridge, England) 1996;123():81-93.

D A Kane; H M Maischein; M Brand; F J van Eeden; M Furutani-Seiki; M Granato; P Haffter; M Hammerschmidt; C P Heisenberg; Y J Jiang; et al. The zebrafish early arrest mutants. Development (Cambridge, England) 1996;123():57-66.

D A Kane; M Hammerschmidt; M C Mullins; H M Maischein; M Brand; F J van Eeden; M Furutani-Seiki; M Granato; P Haffter; C P Heisenberg; et al. The zebrafish epiboly mutants. Development (Cambridge, England) 1996;123():47-55.

P Haffter; M Granato; M Brand; M C Mullins; M Hammerschmidt; D A Kane; J Odenthal; F J van Eeden; Y J Jiang; C P Heisenberg; et al. The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio. Development (Cambridge, England) 1996;123():1-36.

C Nüsslein-Volhard Gradients that organize embryo development. Scientific American 1996;275(2):54-5; 58-61.

D Ferrandon; L Elphick; C Nüsslein-Volhard; D St Johnston Staufen protein associates with the 3’UTR of bicoid mRNA to form particles that move in a microtubule-dependent manner. Cell 1994;79(7):1221-32.

C Nüsslein-Volhard Of flies and fishes. Science (New York, N.Y.) 1994;266(5185):572-4.

S Schulte-Merker; M Hammerschmidt; D Beuchle; K W Cho; E M De Robertis; C Nüsslein-Volhard Expression of zebrafish goosecoid and no tail gene products in wild-type and mutant no tail embryos. Development (Cambridge, England) 1994;120(4):843-52.

S Schulte-Merker; F J van Eeden; M E Halpern; C B Kimmel; C Nüsslein-Volhard no tail (ntl) is the zebrafish homologue of the mouse T (Brachyury) gene. Development (Cambridge, England) 1994;120(4):1009-15.

M C Mullins; M Hammerschmidt; P Haffter; C Nüsslein-Volhard Large-scale mutagenesis in the zebrafish: in search of genes controlling development in a vertebrate. Current biology : CB 1994;4(3):189-202.

M Hammerschmidt; C Nüsslein-Volhard The expression of a zebrafish gene homologous to Drosophila snail suggests a conserved function in invertebrate and vertebrate gastrulation. Development (Cambridge, England) 1993;119(4):1107-18.

F Sprenger; C Nüsslein-Volhard Torso receptor activity is regulated by a diffusible ligand produced at the extracellular terminal regions of the Drosophila egg. Cell 1992;71(6):987-1001.

S Schulte-Merker; R K Ho; B G Herrmann; C Nüsslein-Volhard The protein product of the zebrafish homologue of the mouse T gene is expressed in nuclei of the germ ring and the notochord of the early embryo. Development (Cambridge, England) 1992;116(4):1021-32.

R Geisler; A Bergmann; Y Hiromi; C Nüsslein-Volhard cactus, a gene involved in dorsoventral pattern formation of Drosophila, is related to the I kappa B gene family of vertebrates. Cell 1992;71(4):613-21.

K Arora; C Nüsslein-Volhard Altered mitotic domains reveal fate map changes in Drosophila embryos mutant for zygotic dorsoventral patterning genes. Development (Cambridge, England) 1992;114(4):1003-24.

K Isoda; S Roth; C Nüsslein-Volhard The functional domains of the Drosophila morphogen dorsal: evidence from the analysis of mutants. Genes & development 1992;6(4):619-30.

D Stein; C Nüsslein-Volhard Multiple extracellular activities in Drosophila egg perivitelline fluid are required for establishment of embryonic dorsal-ventral polarity. Cell 1992;68(3):429-40.

D St Johnston; C Nüsslein-Volhard The origin of pattern and polarity in the Drosophila embryo. Cell 1992;68(2):201-19.

D St Johnston; D Beuchle; C Nüsslein-Volhard Staufen, a gene required to localize maternal RNAs in the Drosophila egg. Cell 1991;66(1):51-63.

R Lehmann; C Nüsslein-Volhard The maternal gene nanos has a central role in posterior pattern formation of the Drosophila embryo. Development (Cambridge, England) 1991;112(3):679-91.

S Roth; Y Hiromi; D Godt; C Nüsslein-Volhard cactus, a maternal gene required for proper formation of the dorsoventral morphogen gradient in Drosophila embryos. Development (Cambridge, England) 1991;112(2):371-88.

D Stein; S Roth; E Vogelsang; C Nüsslein-Volhard The polarity of the dorsoventral axis in the Drosophila embryo is defined by an extracellular signal. Cell 1991;65(5):725-35.

C Nüsslein-Volhard Determination of the embryonic axes of Drosophila. Development (Cambridge, England). Supplement 1991;1():1-10.

L M Stevens; H G Frohnhöfer; M Klingler; C Nüsslein-Volhard Localized requirement for torso-like expression in follicle cells for development of terminal anlagen of the Drosophila embryo. Nature 1990;346(6285):660-3.

W Driever; V Siegel; C Nüsslein-Volhard Autonomous determination of anterior structures in the early Drosophila embryo by the bicoid morphogen. Development (Cambridge, England) 1990;109(4):811-20.

S Roth; D Stein; C Nüsslein-Volhard A gradient of nuclear localization of the dorsal protein determines dorsoventral pattern in the Drosophila embryo. Cell 1989;59(6):1189-202.

W Driever; J Ma; C Nüsslein-Volhard; M Ptashne Rescue of bicoid mutant Drosophila embryos by bicoid fusion proteins containing heterologous activating sequences. Nature 1989;342(6246):149-54.

W Driever; G Thoma; C Nüsslein-Volhard Determination of spatial domains of zygotic gene expression in the Drosophila embryo by the affinity of binding sites for the bicoid morphogen. Nature 1989;340(6232):363-7.

F Sprenger; L M Stevens; C Nüsslein-Volhard The Drosophila gene torso encodes a putative receptor tyrosine kinase. Nature 1989;338(6215):478-83.

W Driever; C Nüsslein-Volhard The bicoid protein is a positive regulator of hunchback transcription in the early Drosophila embryo. Nature 1989;337(6203):138-43.

C Nüsslein-Volhard; S Roth Axis determination in insect embryos. Ciba Foundation symposium 1989;144():37-55; discussion 55-64, 92-8.

D St Johnston; W Driever; T Berleth; S Richstein; C Nüsslein-Volhard Multiple steps in the localization of bicoid RNA to the anterior pole of the Drosophila oocyte. Development (Cambridge, England) 1989;107 Suppl():13-9.

U Mayer; C Nüsslein-Volhard A group of genes required for pattern formation in the ventral ectoderm of the Drosophila embryo. Genes & development 1988;2(11):1496-511.

M Klingler; M Erdélyi; J Szabad; C Nüsslein-Volhard Function of torso in determining the terminal anlagen of the Drosophila embryo. Nature 1988;335(6187):275-7.

W Driever; C Nüsslein-Volhard The bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner. Cell 1988;54(1):95-104.

W Driever; C Nüsslein-Volhard A gradient of bicoid protein in Drosophila embryos. Cell 1988;54(1):83-93.

C Nüsslein-Volhard; H G Frohnhöfer; R Lehmann Determination of anteroposterior polarity in Drosophila. Science (New York, N.Y.) 1987;238(4834):1675-81.

H G Frohnhöfer; R Lehmann; C Nüsslein-Volhard Manipulating the anteroposterior pattern of the Drosophila embryo. Journal of embryology and experimental morphology 1986;97 Suppl():169-79.



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